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- Man Bites Dog: Former Merck CEO Blasts High Drug Prices
- Most pharmaceutical companies insist that high drug prices are a natural consequence of the risky business of drug discovery, and that huge profits on marketed drugs are necessary to cover the costs of the 5,000 to 10,000 experimental drugs that fail for every one that succeeds. In fact, there are...
- Blog posts 2008-05-05
- FDA Loosens Rules for Overseas Drug Trials
- Merrill Goozner, a former Chicago Tribune reporter turned public-health advocate (he heads up the Integrity in Science Project at the Center for Science in the Public Interest), notes an interesting and almost wholly overlooked Food and Drug Administration decision that may have the effect of subjecting clinical-trial volunteers in poor...
- Blog posts 2008-05-08
- Life Without Blockbusters: What Valeant's Woes Portend for Pharma
- It's now a truism that the drug industry's "blockbuster model" has pretty much had its day. Much of Big Pharma is having a terrible time winning approval for new drugs and even keeping up sales of existing blockbusters, in part because their underlying rationale -- that pushing drugs into mass...
- Blog posts 2008-05-05
- Glaxo Makes Like Ponce de Leon With Sirtris Buy
- You can't fault GlaxoSmithKline for temerity. The U.K. drugmaker's unexpectedly large $720 million bid for Sirtris Pharmaceuticals represents a gutsy bet that the Massachusetts biotech really has a handle on a class of drugs that slow aging. Not that anyone at either company is eager to describe their work that...
- Blog posts 2008-04-22
- New Lows in Health Insurance -- Pay More for Drugs, If You Can Afford Them
- The basic social bargain of health insurance -- that we all pay premiums while we're healthy so insurance will cover our costs when we're sick -- has been breaking down for close to two decades. To see how high drug prices are shredding it further, look no further than today's...
- Blog posts 2008-04-14
- Pfizer Leads in Layoffs While Drug Prices Soar
- Big Pharma continues to lend new meaning to the phrase "doing more with less," because while the industry seems to get smaller every day, drugmakers are still pushing through big price increases on their leading products. Over at Pharmalot, Ed Silverman provides a helpful roundup tracking the...
- Blog posts 2008-04-10
- Marketing Trumps Science in Vytorin Scandal
- In one of the drug industry's more revealing scandals in a while, Merck and Schering-Plough are struggling to rescue two new cholesterol drugs from evidence that they're useless at fighting heart disease and charges that the two companies deliberately sat on the bad news for roughly a year. ...
- Blog posts 2008-04-01
- Marketing Trumps Science in Vytorin Scandal
- In one of the drug industry's more revealing scandals in a while, Merck and Schering-Plough are struggling to rescue two new cholesterol drugs from evidence that they're useless at fighting heart disease and charges that the two companies deliberately sat on the bad news for roughly a year. ...
- Blog posts 2008-04-01
- HTG
- High Throughput Genomics, Inc., (HTG), is a provider of transcriptomic technology and services. HTG's technology opens a new era of drug discovery and allows companies to identify new drug compounds, quickly eliminate less promising compounds and bring new drugs to market faster. Researchers and scientists are often jaded by biotech...
- Case studies
- Glaxo Wellcome: Fighting Disease and Improving Health
- Intent on improving its ability to bring new drugs to market, global pharmaceutical company Glaxo Wellcome embarked on a comprehensive redesign of its clinical development processes. Glaxo Wellcome aims to be the leading global company in fighting disease and improving health. Its R&D organization spends in the region of $2...
- Case studies
- Brain Steroids: Ban Or Boost?
- Drugs are bad for productivity, right? Well, maybe not. While you can probably correlate productivity increases with declines in per capita drinking, what about coffee (or Diet Coke)? These can act as mild stimulants. Then there's full-fledged brain steroids, say, a drug like Provigil, which...
- Blog posts 2008-03-24
- Improving Public Health Through Human Drugs
- The best-known job for the Center for Drug Evaluation and Research is to evaluate new drugs for safety and effectiveness before they can be sold. The evaluation, called a review, makes sure the drugs approved meet the tough standards for safety, effectiveness quality. Once drugs are on the market, it...
- White papers 2005-08-22
- Counterfeit Drugs: A Growing Public Health Risk in Need of a Multi-Factored Solution
- Counterfeit drugs are those drugs that have been tampered with such that they are not what they purport to be. These drugs can be sub-potent, super-potent, contain only inactive ingredients, contain no medication whatsoever, or have false labels. While counterfeit drugs are a huge problem particularly in developing countries, the...
- White papers 2005-05-01
- Promiscuous Drugs Compared to Selective Drugs (Promiscuity Can Be a Virtue)
- The word selectivity describes a drug's ability to affect a particular cell population in preference to others. As part of the current state of art in the search for new therapeutic agents, the property of selectivity is a mode of action thought to have a high degree of desirability. Consequently...
- White papers 2005-04-26
- Medicare Chemotherapy Payments: New Drug and Administration Fees Are Closer to Providers' Cost
- This U.S. Government Accountability Office (GAO) report, reviews the adequacy of Medicare payments for chemotherapy-related drugs and chemotherapy administration services in 2004 and 2005, and assesses the changes in these payments and compared the payments to the estimated costs of providing these services. The report summarizes that by estimation, Medicare...
- White papers 2004-12-01
- Pricing Drugs in a Regulated Market: A Bargaining Approach
- The model described in this paper is very general and can be used to set the price for new drugs, i.e. for active principles that have no therapeutical alternatives or for drugs that are only partially innovative, i.e. a less effective alternative already exists on the market. The authors assume...
- White papers 2004-11-12
- Immunotoxicity and Hypersensitivity Assessment of New Pharmaceuticals
- Adverse effects of drugs on the immune system have become a matter of increasing concern to the scientific, industrial and public community in recent years. In this respect immune deregulation suppression/enhancement), allergic reactions, and autoimmune disorders can be of relevance. The growing awareness of the possible unwanted immune-modulating effects of...
- White papers 2004-07-21
- Internet Pharmacies: Some Pose Safety Risks for Consumers
- As the demand for and the cost of prescription drugs rise, many consumers have turned to the Internet to purchase drugs. Recent reports of unapproved and counterfeit drugs sold over the Internet have raised further concerns. This report examines the extent to which certain drugs can be purchased over the...
- White papers 2004-06-01
- Retail Prescription Drug Spending in the National Health Accounts
- The rapid spending growth for retail drugs has largely arisen from increased use of new drugs, rather than from increasing prices of existing drugs. A sizable shift in the payment from consumers to third parties has also contributed to faster growth. Strategies such as negotiating for rebates and using tiered...
- White papers 2004-02-01
- Lilly Plans To Donate Rights To TB Drugs To Poor Nations
- Alliances and collaborations for the benefit of humanity seems little out of business but still does have its value, this case study pertains to Eli Lilly & Co., which is casting old drugs in new roles to fight tuberculosis, a perennial killer. It plans to donate rights to TB drugs...
- Case studies 2003-06-05
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