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204 Resources for

Harvard College

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Tumor Detection by Virtual Cystoscopy With Color Mapping of Bladder Wall Thickness: This study determines the value of color mapping of bladder wall thickness for detection of tumor as a component of virtual cystoscopy. Thin axial computerized tomography of the air distended bladder shows promise as a potential screening tool for bladder cancer. The low specificity of color mapped 3D renderings makes...; Tags: PRODUCTIVITY, 3D rendering, wall, patient, 3D, technique, tool; Case studies
Cortical Gray Matter Segmentation Using an Improved Watershed Transform: An accurate segmentation of white matter, gray matter and cerebrospinal fluid (CSF) in MR images of the brain is the key to understanding important brain diseases. It presents a new system for segmentation of MR images of the brain, based on a novel modification of the watershed transform. Their proposed...; Tags: segmentation; White papers
Automatic Nonrigid Registration for Tracking Brain Shift During Neurosurgery: Intraoperative imaging is used more frequently today since this enables the surgeon to localize structures inside the brain more accurately and helps to detect shape changes. In order to combine information's derived at different time points, it describes a nonrigid registration algorithm that aligns MR scans of the brain. Based...; Tags: Document management, imaging; White papers
An Interactive Virtual Endoscopy Tool: This paper presents the design and implementation of a 3D Virtual Endoscopy system for facilitating diagnostic and surgical planning phases of endoscopic procedures. The system allows the user to interactively explore the internal surface of a 3D patient-specific anatomical model and to create and update a fly-through trajectory through the...; Tags: 3D, patient; White papers
MR-Based Three-Dimensional Modeling of the Normal Pelvic Floor in Women: The objective of this paper was to use a combination of axial MRsource images and three-dimensional (3D) models to describe the anatomy of the normal pelvic floor in young nulliparous women and to measure the volume of the levator ani. In all volunteers, the signal intensity of the puborectalis exceeded...; Tags: Gender and diversity, women, 3D; White papers

Unsupervised and Adaptive Segmentation of Multispectral 3D Magnetic Resonance Images of Human Brain: A Generic Approach: This paper provides a generic algorithm for the segmentation of three dimensional multi-spectral magnetic resonance images. The algorithm is unsupervised and adaptive, does not require initialization, classifies the data in any number of tissue classes and suggests an optimal number of classes. It uses a statistical model including Bayesian distributions...; Tags: Engineering, segmentation, intensity, algorithm, Bayesian; White papers
Three-dimensional Optical Flow Method for Measurement of Volumetric Brain Deformation From Intraoperative Magnetic Resonance Images: A three-dimensional optical flow method to measure volumetric brain deformation from sequential intraoperative Magnetic Resonance Images (MRIs) and preliminary clinical results from five cases are reported. Intraoperative MRIs were scanned before and after dura opening, twice during tumor resection, and immediately after dura closure. The maximum cortical surface shift measured...; Tags: Harvard College; White papers
Surface Based Atlas Matching of the Brain Using Deformable Surfaces and Volumetric Finite Elements: The automatic identification and localization of structures in magnetic resonance (MR) brain images are a major part of the processing work for the neuro-radiologist in numerous clinical applications, such as functional mapping and surgical planning. To aid in this task, a considerable amount of research has been directed toward the...; Tags: 3D; White papers
Double Cervix and Vagina With Septate Uterus: An Uncommon Mullerian Malformation: A 20-year-old nulligravid female was found to have a septate uterus with double cervix and a vagina with partial longitudinal vaginal septum. The anomaly presented symptomatically, was suggested by clinical examination, and confirmed by Magnetic Resonance Imaging (MRI) and intra-operative visualization. Visualization of the anomaly was enhanced by MR-based three...; Tags: anomaly, magnetic resonance imaging, visualization, 3D, technique; Case studies
Discrimination of Relapsing and Progressive MS Through MRI Estimates of Brain Parenchymal Fraction and Lesion Burden: The objective of this paper is to evaluate the relationship between white matter lesions and brain atrophy in relapsing and progressive multiple sclerosis (MS). The different rate of BPF loss (atrophy) and the different relationship between atrophy and changes in lesion burden support the hypothesis that different pathogenetic mechanisms underly...; Tags: Microsoft Corp., Fluctuation, Harvard College; White papers
2D-3D Rigid Registration of X-Ray Fluoroscopy and CT Images Using Mutual Information and Sparsely Sampled Histogram Estimators: The registration of pre-operative volumetric datasets to intra-operative two-dimensional images provides an improved way of verifying patient position and medical instrument location. In applications from orthopedics to neurosurgery, it has a great value in maintaining up-to-date information about changes due to intervention. This paper proposes a mutual information-based registration algorithm...; Tags: patient, strategy; White papers
An Image Processing Strategy for the Quantification and Visualization of Exercise Induced Muscle MRI Signal Enhancement: Exercise increases the skeletal muscle water signal in T2-weighted images. Potential medical applications of MR studies of exercise induced muscle signal intensity changes are the assessment of myopathies, sport training regimens, and physical therapy approaches following surgeries. We developed an automated image processing technique which provides volumetric analysis and visualization...; Tags: Network technology, image processing, T2, therapy, visualization, 3D, training, analysis; White papers
Fast and Accurate Redistancing for Level Set Methods: Although the Level Set Method has only recently been introduced as an image processing tool, it has already proved useful in delineating contours and in segmenting objects. However, since this method represents contours with images, processing time may increase considerably. To offset this problem, it is common to create a...; Tags: image processing; White papers
Why We Aren't As Ethical As We Think We Are: A Temporal Explanation: This paper explores the biased perceptions that people hold of their own ethicality. We argue that the temporal trichotomy of prediction, action and evaluation is central to these misperceptions: People predict that they will behave more ethically than they actually do, and when evaluating past (un)ethical behavior, they believe they...; Tags: Harvard College; White papers 2007-08-27
Designing A Two-Sided Platform: When To Increase Search Costs?: This paper proposes a model for analyzing an intermediary's incentives to increase the search costs incurred by consumers looking for sellers (stores). First, we show that the quality of the search service offered to consumers is more likely to be degraded (i.e. the probability that consumers find their favorite store...; Tags: Sales force management, intermediary, incentive, revenue, search technology; White papers 2007-08-29
Exclusivity And Control: We analyze platform competition for content in the presence of strategic interactions between content distributors and content providers. We provide a model of bargaining and price competition within these industries, and show that whether or not a piece of content ends up exclusive to one platform depends crucially on whether...; Tags: Pricing, content provider, pricing strategy, industry; White papers 2007-08-26
Innovation Through Global Collaboration: A New Source Of Competitive Advantage: This paper describes the results of a study to understand the strategies and practices used by firms that achieve greater success in their collaborative innovation efforts. We found many firms mistakenly applied an "Outsourcing" mindset to collaboration efforts which, in turn, led to three critical errors: First, they focused solely...; Tags: Groupware, collaboration, competitive advantage, outsourcing, supplier, strategy; White papers 2007-08-14
Film Rentals And Procrastination: This paper report on a field study demonstrating systematic differences between the preferences people anticipate they will have in the future and their subsequent revealed preferences. We examine the film rental and return patterns of a sample of online DVD rental customers over a period of four months. We predict...; Tags: Consumer electronics, DVD; White papers 2007-07-05
Self-Regulatory Institutions For Solving Environmental Problems: Scholars of management have long considered how institutions can help resolve market imperfections and thereby improve human welfare. Most previous research has emphasized the use of for-profit firms. Such institutions cannot effectively address many environmental problems, however, because environmental problems often transcend firm boundaries. As a result, management scholars have...; Tags: Scholar, Harvard College, Institution; White papers 2007-07-01
Hedge Fund Investor Activism And Takeovers: This paper examines long-horizon stock returns around hedge fund activism in a comprehensive sample of 13D filings by portfolio investors between 1993 and 2006. Abnormal returns surrounding investor activism are high for the subset of targets that are acquired ex-post, but not detectably different from zero for targets that remain...; Tags: Investment, activism, hedge fund, activist, M&A, stock; White papers 2007-07-01