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ACM

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Market Cap:$3.0B
Last Fiscal Year Sales:$18.8M
  • Public
  • UK
Dow Jones Description

Acambis is a leading biotechnology company targeting infectious diseases with novel vaccines. Acambis' development-stage pipeline includes vaccines that could either offer improvements over existing products or target unmet medical needs. Its investigational vaccine against Japanese encephalitis, ChimeriVax-JE, which has shown excellent safety and efficacy profile in Phase 3 clinical testing and is currently undergoing paediatric trials in India, is intended to provide an "ideal' vaccine to address the estimated 50,000 cases of this viral disease in Asia every year. Acambis' proprietary ChimeriVax technology, developed in association with St Louis University, has also been used to develop ChimeriVax-West Nile, which is undergoing Phase 2 clinical testing, making it the most advanced investigational vaccine against the West Nile virus. Acambis also has the only vaccine in development against Clostridium difficile bacteria, a leading cause of hospital-acquired infections. Recognised internationally as the leading producer of smallpox vaccines, Acambis manufactured its smallpox vaccine, ACAM2000, for emergency-use stockpiles held by the US Government and several other governments around the world under a US FDA IND application. ACAM2000 is licensed for active immunisation of persons determined to be at high risk for smallpox infection.

Non-Executive Director
John Lambert
Number of Employees 206
Contact Information

Peterhouse Technology Park

Cambridge, CB1 9PT

www.acambis.com

(44) 1223275300

NAICS Code Human Resources Consulting Services: 541612

Recent Events

  • Venturing into vaccines

    9/28/08 - Licensing / Contract - View Story

  • Genmab, Glaxo cancer drug beats target in key test

    7/31/08 - Merger / Acquisition - View Story

  • French drug firm expands in Mass.

    7/26/08 - Merger / Acquisition - View Story

  • Sanofi Building Vaccine Pipeline with $549M Buyout of Acambis

    7/25/08 - Merger / Acquisition - View Story

  • UBS job cuts ... BAA to escape fines ... Eat sale

    4/07/08 - Joint Venture / Alliance - View Story

  • Acambis extends vaccine licensing agreement with Sanofi Pasteur

    3/24/08 - Joint Venture / Alliance - View Story

  • Sector Wrap: Drug Makers Mostly Rise

    11/13/07 - Joint Venture / Alliance - View Story

  • New Acambis CEO Vows To Revitalize Its Pipeline

    10/02/07 - Joint Venture / Alliance - View Story

  • Acambis Smallpox Vaccine Finally Wins U.S. Approval

    9/05/07 - Buildings Purchased - View Story

  • Officials at Acambis announce latest news and research developments

    7/27/07 - Mgmt. Change Entering - Other - View Story

  • Bavarian Nordic and Acambis Settle all Legal Disputes on MVA

    7/26/07 - Legal Settlement - View Story

  • 3rd UPDATE: Acambis In Senior Management, Cost-Cutting Overhaul

    3/08/07 - Bond / Stock Rating - View Story

  • Acambis Names New Chief Executive, Ousts CFO, Restructures to Slash Costs

    3/07/07 - Mgmt. Change - Entering - View Story

  • Acambis PLC - Board Appts, MVA Update

    11/28/06 - Mgmt. Change - Entering - View Story

  • Acambis Says U.S. Decided Not to Order Its Smallpox Vaccine; Shares Plunge

    11/14/06 - Lawsuit Filed - View Story

News & Analysis

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Decision Makers

Name (plus bio) Position
John Lambert Non-Executive Director
Randal Chase Non-Executive Director
Dr William Jenkins Non-Executive Director
Gordon Cameron OBE Chief Executive Officer
David Lawrence Chief Financial Officer
Elizabeth Jones Chief Financial Officer
Michael Watson Executive Vice President, Research and Development
David M. Wonnacott Senior Vice President, Regulatory Affairs and Quality Systems
Donna Radzik Senior Vice President, Operations
Clement Lewin Vice President, Marketing, Policy and Strategy
Harry Kleanthous Vice President, Research
Lyndsay Wright Vice President, Communications and Investor Relations
Marc Collett Vice President of Research
Marc Collette Vice President, Res
Alan J. Dalby Non-Executive Director
Anna Gavrilova Communications and Ir Officer

Board of Directors

Name (plus bio) Position
Thomas Monath Board of Directors
Peter Fellner Chairman
Ross Graham Board of Directors
Gordon Cameron Board of Directors
Alan Smith Chairman

Organization Position Status
Chiron Vice President Current
Gavi Representative Current
Acambis plc Non-Executive Director Current
Cambridge Biostability Limited Chairman Current
Novavax, Inc. Chairman Current
aventis Group Former
Novavax, Inc. Board of Directors Current
Acambis plc Board of Directors Former

Organization Position Status
Xcellerex, Inc. Partner, Kleiner Perkins Caufield & Byers Current
Harvard School of Public Health Adjunct Professor Current
Acambis plc Board of Directors Current
Xcellerex, Inc. Board of Directors Current
Acambis Inc. Chief Scientific Officer Former
Acambis Inc. Executive Director Former
Acambis plc Medical Doctor Former
Acambis plc Executive Director & Chief Scientific Officer Former
Harvard Medical School M.D. Former
Harvard College Undergraduate Degree Former

Organization Position Status
University of Oxford Director, Technology Transfer Group Current
Consort Medical plc Chairman Current
Acambis plc Chairman Current
Astex Therapeutics Limited Chairman Current
Vernalis Executive Chairman Current
Vernalis plc Chairman Current
Bespak Plc Board of Directors Current
Evotech, Inc. Board of Directors Current
UCB, S.A. Director Current
Evotec AG Director Current
Isis Innovation, Ltd. Director Current
Biotie Therapies Corp Board of Directors Current
QinetiQ Inc. Board of Directors Current
QinetiQ Group plc Director Current
UCB Pharma Inc. Director Current
Celltech Group Plc Chief Executive Officer Former
Acambis plc Board of Directors Former
Cell-Tech, Inc. Former
Premier Research Group plc Chairman Former
Celltech Group Plc Chairman Former
Consort Medical plc Board of Directors Former

Dr. Chase has a wealth of experience in vaccines and has spent his entire career (30 years) in the biotechnology and$ pharmaceutical sectors. Past positions include President of Shire Biologics, Senior Vice President Vaccines Operations of Biochem Pharma, President & CEO of North American Vaccine, President & CEO of Pasteur Merieux Connaught, President & CEO of Quadra Logic Technologies Inc., Senior Vice President of Glaxo Canada Inc., and Director of Bristol Meyers. Dr. Chase is active as a Board member with several companies and has many contacts in the biotechnology sector which will serve IVT well in the future through potential collaborations and networking opportunities. His initial appointment with IVT as President & CEO is on a part-time interim basis as the Company is at an early-stage of development for human vaccines.

Organization Position Status
Immunovaccine Technologies Inc CEO Current
Acambis plc Non-Executive Director Current
Medicago Inc Chairman of The Board and Director Current
Molecular Templates Inc Executive Chairman Current
Bioject Medical Technologies Inc. Director Current
Conjuchem Inc Director Current
Immunovaccine Technologies Inc Board of Directors Current
Immunovaccine Technologies Inc President Former
TSX Group, Inc. Former
University of British Columbia Ph.D. In Biochemistry Former
Acambis plc Board of Directors Former
London Business School Former

Ross Graham, aged 58, was appointed to the Board of Acambis as a Non-executive Director on 25 March 2004. The Board considers him to be an independent Non-executive Director. He is Chairman of the Audit Committee and has been identified by the Board as having recent and relevant financial experience. Ross was most recently Corporate Development Director of Misys plc, which he joined as Finance Director in 1987 at the time of its flotation, and was appointed Corporate Development Director in 1998 with Board responsibility for corporate transactions and management of strategic alliances. He stepped down from Misys' Board of Directors at the end of 2003 after more than 16 years. Prior to his career at Misys, Ross was a Partner with Arthur Young, a predecessor firm to Ernst & Young, where he qualified as a Chartered Accountant. He is also a Non-executive Director of Wolfson Microelectronics plc, Psion plc, and Patientline plc, and Non-executive Chairman of Vecta Software Corporation Ltd. Mr Graham attends numerous courses and lectures on audit, financial, remuneration and non-executive related matters.

Organization Position Status
Acambis plc Non-Executive Director Current
Wolfson Microelectronics Plc Non-Executive Director Current
Psion Plc Non-Executive Director Current
Vecta Software Corporation, Inc. Non-Executive Chairman Current
Psion Teklogix Inc Board of Directors Current
Wolfson Microelectronics Plc Board of Directors Current
Patientline Plc Board of Directors Current
Psion Plc Board of Directors Current
Arthur Young, Inc. Partner Former
Acambis plc Board of Directors Current

William J. Jenkins has been a non-executive director since July 2000. He serves on the Audit and Nominating and Corporate Governance Committees. Until March 1999, Dr. Jenkins was the Head of Clinical Development and Regulatory Affairs Worldwide and a member of the Executive Committee at Novartis Pharma AG in Switzerland. Dr. Jenkins is a consultant to the pharmaceutical industry and to private equity and venture capital firms and a non-executive director of BTG plc, Consort Medical plc, Vaximm AG and Monogram Biosciences, Inc. He is Chairman of the Scientific Advisory Board of Evotec AG and a member of the Scientific Advisory Boards of BB Biotech Ventures II and Nicholas Piramal India Ltd. Dr. Jenkins holds a B.A., M.D., and other advanced degrees from Cambridge University in England, as well as advanced degrees from the Royal College of Physicians, United Kingdom and from London University.

Organization Position Status
Consort Medical plc Consultant Current
Acambis plc Non-Executive Director Current
Evotech, Inc. Chairman Current
Eurand N.V. Board of Directors Current
Evotec AG Board of Directors Current
Consort Medical plc Board of Directors Current
Eurand America, Inc. Board of Directors Current
Tanox, Inc. Board of Directors Current
Bb Biotech Ventures Board of Directors Current
Btg Plc Board of Directors Current
Epigenesis Pharmaceuticals, LLC Board of Directors Current
Acambis plc Board of Directors Current
Esbatech AG Board of Directors Current
Monogram Biosciences, Inc. Board of Directors Current
Monogram Biosciences, Inc. Member Current
Tanox, Inc. Member Current
Btg Non-executive Director Former
Novartis AG Former
Evotech, Inc. Board of Directors Former
Royal College M.D. Former
University of Cambridge Ba and Md Degrees Former
Cambridge University M.D. Former
Cambridge University B.A. Former
Royal College B.A. Former
Cambridge University Degrees Former
Royal College Degrees Former
University of London Former

Organization Position Status
Acambis plc CEO Current
Acambis plc Board of Directors Current
Ernst & Young Former
London Stock Exchange plc Former

Organization Position Status
Acambis plc Chief Executive Officer Current

Organization Position Status
Acambis plc Chief Financial Officer Current
Chiron Vice President Former
Acambis plc Board of Directors Former

Organization Position Status
Acambis plc Chief Financial Officer Current
Acambis plc Board of Directors Former

Organization Position Status
Acambis plc Executive Vice President, Research and Development Current
Acambis plc Board of Directors Former

Organization Position Status
Acambis plc Senior Vice President, Regulatory Affairs and Quality Systems Current
Aviron Vice President of Regulatory Affairs Former
Inhibitex, Inc. Vice President of Regulatory Affairs and Quality Former
Merck & Co. Inc. Former
Utah State University Ph.D. In Biochemistry Former
Brigham Young University B.S. in Chemistry Former
Brigham Young University B.S. in Chemistry Former

Organization Position Status
Acambis plc Senior Vice President, Operations Current
Purdue University PhD In Analytical Chemistry Former

Organization Position Status
Acambis plc Vice President, Marketing, Policy and Strategy Current
PRTM, LLC consultant Former
Edinburgh University Fellow Former
University of London Consultant Former
Edinburgh University Mba Former

Organization Position Status
Acambis plc Vice President, Research Current
University of London Ph.D. Former

Lyndsay Wright is Vice President of Communications and Investor Relations. She joined Acambis in 2001 to establish the Communications function and oversees both internal and external communication activities, including investor relations, media relations and employee communications. Prior to joining to Acambis, Lyndsay worked in the Communications department of Associated British Ports Holdings PLC.

Organization Position Status
Acambis plc Vice President, Communications and Investor Relations Current
Associated British Ports Holdings Plc Former

Dr. Marc S. Collett joined Acambis in November 2005 as Vice President of Research. He has over 25 years experience in the biotechnology/biopharmaceutical industry and has participated in the discovery and development of vaccines, monoclonal antibodies and pharmaceuticals through NDA filing. Prior to Acambis, Dr. Collett co-founded ViroPharma Incorporated and served as its Vice President of Discovery Research for 10 years. Before that, Dr. Collett served in various Research Director positions at PathoGenesis Corporation, MedImmune, Inc. and Molecular Genetics, Inc. Dr. Collett has also served on the faculty of the Department of Microbiology, University of Minnesota Medical School and the Department of Large Animal Clinical Sciences, University of Minnesota College of Veterinary Medicine. Dr. Collett received his PhD in molecular and cell biology from the University of Michigan.

Organization Position Status
Acambis plc Vice President of Research Current
Alphavax, Inc Board of Directors Current
University of Minnesota Medical School Faculty Former
Acambis Inc. Vice President of Research Former
ViroPharma Incorporated Co-Founder Former
MedImmune, Inc. Research Director Former
University of Michigan PhD Degrees Former
University of Michigan BS Former

Organization Position Status
Acambis plc Vice President, Res Current

Alan Dalby, aged 69, became a Non-executive Director of Acambis on 1 May 1998. He is the Senior Independent Non-executive Director and Chairman of the Remuneration Committee. The Board considers Alan to be an independent Non-executive Director. Alan was previously an Executive Director of SmithKline, a predecessor company to GlaxoSmithKline plc, and retired from the role of Chairman of Reckitt Benckiser plc in 2001. He is a Director of Alteon, Inc., a US-based biotechnology company.

Organization Position Status
Acambis plc Non-Executive Director Current
Legendary Pharmaceuticals Current
Reckitt Benckiser, Inc. Chairman Current
Alteon Inc. Director Current
GlaxoSmithKline Plc executive director Former
Reckitt Benckiser plc Chairman Former
Acambis plc Board of Directors Former

Organization Position Status
Acambis plc Communications and Ir Officer Current

Alan is a member of the Chartered Institute of Public Finance and Accountancy. He joined the Board of Acambis plc as a Non-executive Director in 1995 and was appointed Non-executive Chairman in 1999. He was Group Managing Director of Anglian Water plc until December 1997 and is currently Chairman of Avlar BioVentures Limited.

Organization Position Status
Acambis plc Chairman Current
Avlar Bioventures Limited Chairman Current
Cenes Limited Board of Directors Current
Cenes Pharmaceuticals PLC Board of Directors Current
ACM $26.99 0.770 (2.94% )
Volume 2,043,207
Shares Outstanding 112.6M
Market Cap 3.0B
Year High 33.2
Year Low 9.999
Earnings Per Share 1.720
P/E Ratio 15.
Dividend 0.000
Yield 0.00
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