BNET Industries

Market Cap:$10.8M
  • Public
  • US
Dow Jones Description

Alfacell Corporation is the first company to advance a biopharmaceutical product candidate that works in a manner similar to RNA interference (RNAi) through late-stage clinical trials. The product candidate, ONCONASE, is an RNase that overcomes the challenges of targeting RNA for therapeutic purposes while enabling the development of a new class of targeted therapies for cancer and other life-threatening diseases. In addition to an ongoing Phase IIIb study in malignant mesothelioma, Alfacell is conducting a Phase I/II trial of ONCONASE in non-small cell lung cancer (NSCLC) and other solid tumors. ONCONASE is a first-in-class therapeutic based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells while sparing normal cells. ONCONASE triggers apoptosis, the natural death of cells, via multiple molecular mechanisms of action. Alfacell's proprietary drug discovery program is also the basis for the development of recombinant designed RNases for chemical conjugation and fusion (gene and protein) products with various targeting moieties, such as monoclonal antibodies, growth factors, and cytokines. This program also provides for joint design and development of new products with outside partners seeking line-extensions and/or improvements of the therapeutic effectiveness of their existing products. ...

President, CFO & COO
Charles Muniz
Number of Employees 15
Contact Information

300 Atrium Dr

Somerset, New Jersey 08873

www.alfacell.co...

(732) 652-4525

NAICS Code Biological Product (except Diagnostic) Manufacturing: 325414

News & Analysis

alfacell corp. - All News and Analysis

  • Alfacell Corporation F3Q08 (Qtr End 04/30/2008) Earnings Call Transcript

    Seeking Alpha - 2008-06-11

    Question-and-Answer Session Operator Operator Instructions Your first question comes from Stephen Dunn - Dawson James. Stephen Dunn - Dawson James Do you have your results of 122 patients? Do you have a hypothesis of the mechanism of actions for ONCONASE and why it would work...

    Tags: Alfacell Corp.

  • Alfacell Corp. F2Q08 (Qtr End 1/31/08) Earnings Call Transcript

    Seeking Alpha - 2008-03-07

    Question-and-Answer SessionOperator Operator Instructions Our first question comes from the line of Raymond Myers with Emerging Growth Equities. Please go ahead. Raymond Myers - Emerging Growth Equities Thank you and good morning. Tina Shogen Good morning. Raymond Myers - Emerging Growth Equities Good morning, Tina. Let see, well, thank...

    Tags: Alfacell Corp.

  • Alfacell F1Q08 (Qtr End 10/31/07) Earnings Call Transcript

    Seeking Alpha - 2007-12-10

    Question-and-Answer Session Operator Operator Instructions Our first question comes from the line of Stephen Dunn with Dawson James. Please proceed with your question. Stephen Dunn - Dawson James Securities Good morning, Tina and Larry. Thanks for taking my call. Just a couple of questions here; you’ve got additional...

    Tags: Alfacell Corp.

  • Alfacell F4Q07 (Qtr End 7/31/07) Earnings Call Transcript

    Seeking Alpha - 2007-10-15

    Question-and-Answer Session Operator Operator Instructions Our first question is coming from Raymond Myers of Emerging Growth Equities. Raymond A. Myers - Emerging Growth Equities Thank you for taking the questions and congratulations, Tina and Larry, for getting to this point. We are almost to the un-blinding of our...

    Tags: Alfacell Corp.

  • Alfacell Corporation Receives Progressive Following.

    - 2006-12-14

    M2 PRESSWIRE-14 December 2006-www.streetinvesting.com: Alfacell Corporation Receives Progressive FollowingC1994-2006 M2 COMMUNICATIONS LTD RDATE:14122006 Streetinvesting.com is the author of this release. This release is a result of our current concentration on Alfacell Corporation (NASDAQ:ACEL) and their latest corporate developments and market...

    Tags: Alfacell Corp., Federal Reserve Board, FINANCE, investor

Decision Makers

Name (plus bio) Position
Charles Muniz President, CFO & COO
Andrew P Aromando Chief Operating Officer
Diane Scudiery Director, Clinical & Regulatory Operations
Dr Susanna Rybak
Jacob V Maizel
John J Costanzi
Carter Stephen Director
Stephen K. Carter Director

Board of Directors

Name (plus bio) Position
James J Loughlin Chairman
Michele Carbone Chairman
Donald R Conklin Member, Board of Directors
Harvey I Pass Board of Directors
John P Brancaccio Board of Directors
Paul M Weiss Board of Directors
Raja M Flores Board of Directors
Zbigniew Darzynkiewicz Board of Directors

Organization Position Status
Alfacell Corp President, CFO & COO Current
Alfacell Corp Board of Directors Current

Organization Position Status
Alfacell Corp Chief Operating Officer Current
Onconase Senior Vice President, Commercial Development and Operations Current
Sandoz Pharmaceuticals Sales Representative Former
Innovex, Inc. Senior Executive Former
Quintiles Transnational Corp. Senior Executive Former
Rutgers University M.A. Former
The College of New Jersey B.A. Former

Organization Position Status
Alfacell Corp Director, Clinical & Regulatory Operations Current
Onconase Director, Clinical and Regulatory Operations Current
Alfacell Corp Board of Directors Current
Enzon Pharmaceuticals, Inc. Director of Clinical Research Former
Fairleigh Dickinson University M.A. Former
Rutgers University M.Ed. Former
William Paterson University B.A. Former

Organization Position Status
Alfacell Corp Current
Harvard Medical School Assistant Professor of Pathology Former
National Hockey League Former
NCI, Inc. Former

Organization Position Status
Alfacell Corp Current
NCI, Inc. Former

Organization Position Status
Alfacell Corp Current
Thompson Cancer Survival Center Medical Director Former
The University of Texas Director of the Cancer Center Former
University of Texas Medical Branch professor of medicine Former
Georgetown University School of Medicine Residency Former
Wilford Hall Medical Center Former
University of Texas Medical Branch Director Former
Georgetown University M.D. Former

Organization Position Status
Alfacell Corp Chairman Current
KPMG International Former
Alfacell Corp Director Former

Organization Position Status
Alfacell Corp Chairman Current

Stephen K. Carter, M.D. has served on our Board of Directors since September 1998. Since 1997, Dr. Carter has been a consultant to the pharmaceutical industry. Dr. Carter was Senior Vice President of Research and Development at Boehringer Ingelheim Pharmaceuticals, Inc. from 1995 to 1997. Prior to joining Boehringer, Dr. Carter was Senior Vice President of Worldwide Clinical Research and Development at Bristol-Myers Squibb Company. From 1976 to 1982, Dr. Carter served as Director of the Northern California Cancer Program. Dr. Carter was also appointed to President Clinton's panel for AIDS drug development. Dr. Carter is a director of Allos Therapeutics, Alfacell Corporation, Emisphere Technologies, Inc. and Vion Pharmaceuticals Inc. and several privately held companies. Dr. Carter received an A.B. in History from Columbia College and an M.D. degree from New York Medical College. He completed a medical internship and residency at Lenox Hill Hospital.

Organization Position Status
Emisphere Technologies, Inc. Director Current
Vion Pharmaceuticals, Inc. Director Current
Cytogen Corporation Director Current
Alfacell Corp Director Current
Allos Therapeutics, Inc. Director Current
Callisto Pharmaceuticals, Inc. Director Current
Tapestry Pharmaceuticals Inc. Director Current
Celator Pharmaceuticals Director Current
Bristol-Myers Squibb Company Senior Vice President of Worldwide Clinical Research and Development Former
New York Medical College M.D. Degree Former
Columbia College A.B. In History Former

Organization Position Status
Alfacell Corp Member, Board of Directors Current
Bio Transplant Incorporated Member, Board of Directors Current
Cytotherapeutics, Inc. Board of Directors Current
Onconase Board of Directors Current
Vertex Pharmaceuticals Incorporated Board of Directors Current
inVentiv Health Inc. Board of Directors Current
Schering-Plough Corporation Executive Vice President Former
Schering-Plough Corporation Senior Executive Former
Schering-Plough Corporation Chairman, Health Care Products Division Former
Schering-Plough Healthcare Products Corp. Chairman Former
Rutgers University MBA degree Former
Williams College B.A. Former

Organization Position Status
New York University Medical Center Chief of Thoracic Oncology Current
New York University Medical Center Director of the Division Current
Asbestos Corporation Ltd. Director of the Division of Thoracic Surgery Current
Alfacell Corp Board of Directors Current
Rosetta Genomics Ltd. Vice Chairman Current
Onconase Board of Directors Current
Medical University of South Carolina Chief Former
University of Mississippi Medical Center Chief Surgeon Former
Wayne State University Professor Former
Duke University School of Medicine Former
The Johns Hopkins University Former

John P. Brancaccio, a retired CPA, has served as a Director of our company since April 2004. Since April 2004, Mr. Brancaccio has been the Chief Financial Officer of Accelerated Technologies, Inc., an incubator for medical device companies. From May 2002 until March 2004, Mr. Brancaccio was the Chief Financial Officer of Memory Pharmaceuticals Corp., a biotechnology company. From 2000 to 2002, Mr. Brancaccio was the Chief Financial Officer/Chief Operating Officer of Eline Group, an entertainment and media company. Mr. Brancaccio is currently a director of Alfacell Corporation as well as a director of each of Xenomics, Inc. and FermaVir Pharmaceuticals, Inc.

Organization Position Status
Accelerated Technologies Corporation Chief Financial Officer Current
Xenomics, Inc. Director Current
Onconase Board of Directors Current
Fermavir Pharmaceuticals, Inc. Director Current
Alfacell Corp Board of Directors Current
Inhibitex, Inc. Board of Directors Current
Callisto Pharmaceuticals, Inc. Board of Directors Current
Compensation Committees Board of Directors Current
Pawfect Foods Inc Board of Directors Current
Memory Pharmaceuticals Corp. Chief Financial Officer Former
Memory Pharmaceuticals Corp. Secretary and Treasurer Former
Seton Hall University Certified Public Accountant Former
Deven International Former
Memory Pharmaceuticals Corp. Treasurer Former
Seton Hall University Degree In Accounting Former

Organization Position Status
Procertus Biopharm, Inc. Acting President and CEO, Director Current
Gala Biotech President Current
Venture Investors LLC Managing Director Current
Mithridion Board of Directors Current
Alfacell Corp Board of Directors Current
Caden Biosciences Inc. Board of Directors Current
Procertus Biopharm, Inc. Board of Directors Current
Cardinal Health, Inc. President Former
Wyeth Pharmaceuticals, Inc. Director of Licensing Former
Wyeth-Ayerst Laboratories Director of Licensing Former
Wyeth-Ayerst Director of Licensing Former
Venture Investors LLC Analyst Former
University of Wisconsin-Madison M.B.A. Former
Carleton University Bachelor of Science In Biochemistry Former

Organization Position Status
Alfacell Corp Board of Directors Current
Albert Einstein College Former

Stephen K. Carter, M.D., a Director of the Company since 2003, is the former Senior Vice President, Clinical and Regulatory Affairs, of Sugen, Inc. (ownership of Sugen has since passed to Pfizer, Inc. as part of its acquisition of Pharmacia in April 2003). Dr. Carter previously was the Senior Vice President, Research and Development of Boehringer Ingelheim Pharmaceuticals, Inc., now independently owned. Prior to this, he served 13 years at Bristol-Myers Squibb Co., including, as its Senior Vice President, Worldwide Clinical Research and Development. Dr. Carter is a former Deputy Director at the National Cancer Institute (NCI)'s Division of Cancer Treatment and is a member of the American Society of Clinical Oncology. He received his Medical Doctorate from New York Medical College. He is currently a member of the boards of directors of Alfacell Corporation, Achillion Pharmaceuticals, Inc., Cytogen Corporation, Sopherion Therapeutics, Inc., and Vion Pharmaceuticals, Inc.

Organization Position Status
Emisphere Technologies, Inc. Director of the Company Current
Threshold Pharmaceuticals, Inc. Current
Callisto Ltd. Current
Sunesis Pharmaceuticals, Inc. Current
Anisfield-Wolf Book Awards Current
Onconase Board of Directors Current
Allos Therapeutics, Inc. Director Current
Society of Surgical Oncology Board of Directors Current
Amphora Discovery Corporation Board of Directors Current
Cytogen Corporation Director Current
American Association for Cancer Research, Inc. Board of Directors Current
The American Law Institute Board of Directors Current
Emisphere Technologies, Inc. Board of Directors Current
Aspen Institute Board of Directors Current
Tapestry Pharmaceuticals Inc. Director Current
Alfacell Corp Director Current
American Society of Clinical Oncology Board of Directors Current
The Celator Board of Directors Current
Celator Pharmaceuticals Director Current
American Association for Cancer Research, Inc. Member Current
The American Law Institute Member Current
Aspen Institute Trustee Current
Bristol-Myers Squibb Company Senior Vice President, Worldwide Clinical Research and Development Former
United States Court of Appeals for the District of Columbia Circuit Clerk Former
NCI, Inc. Former
New York Medical College M.D. Former
Vion Pharmaceuticals, Inc. Board of Directors Current
Columbia College A.B. Former
Stanford University Bachelor's Degree Former
Columbia University B.A. Former
Yale University Degree Former
New York Medical College Degree Former
Stanford University member Former

Zbigniew Darzynkiewicz, M.D., Ph.D., is the Director of the Brander Cancer Research Institute at the New York Medical College and the Professor of Medicine and Pathology at the same College. Formerly, Dr. Darzynkiewicz was the Professor of Cell Biology and Genetics at Cornell University Medical School, a Member of the Sloan-Kettering Institute for Cancer Research, the Head of the Experimental Cell Research Laboratory, and the Director of the Flow Cytometry Core Facility Network, all at the Sloan-Kettering Institute, New York. Dr. Darzynkiewicz is the Editor of the Experimental Cell Research and Cell Proliferation and a Member of the Editorial Boards of nine other scientific journals. He is the past President of The Cell Kinetics Society and also past President of the International Society for Analytical Cytology (ISAC; with over 2,000 members from over 60 countries). Dr. Darzynkiewicz has authored 400 original publications and over 75 chapters and reviews in books devoted to the subject of cell growth, regulation of the cell cycle and apoptosis, and has authored and/or edited 11 books. He holds five US patents, several are pending. His publications have been cited over 9,000 times in the scientific literature. He consults several pharmaceutical companies and is on the Board of Scientific Advisors of the Alfacell Company (Bloomfield, NJ). Dr. Darzynkiewicz received his M.D. (with highest honors) in 1960 and his Ph.D. in 1966 from the Medical School of Warsaw, Warsaw, Poland. He completed his post-graduate studies at the State University of New York at Buffalo and the Medical Nobel Institute of Karolinska Institute, Stockholm, Sweden. Since 1974, he has been associated with the Sloan-Kettering Institute for Cancer Research, and since 1990, he has been with New York Medical College, Valhalla, New York.

Organization Position Status
Pharmaseq, Inc. Director of the Brander Cancer Research Institute Current
Editorial, LLC Board of Directors Current
New York Medical College Director Current
Alfacell Corp Board of Directors Current
Weill Medical College of Cornell University Professor of Cell Biology and Genetics Former
National Aeronautics and Space Administration Former
New York Medical College Ph.D Former
State University of New York at Buffalo Post - Graduate Former
The State University of New York post-graduate studies Former
Karolinska Institute Former
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     ACEL $0.23 -0.01 (-4.17% )
Average Volume 49,039
Shares Outstanding 47.31M
Market Cap 10.9M
Year High 0.52
Year Low 0.06
Earnings Per Share N/A
P/E Ratio -
Dividend N/A
Yield N/A
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