BNET Industries

Market Cap:$179.7M
Last Fiscal Year Sales:$8.3M
  • Public
  • US
Dow Jones Description

We are a drug discovery and development company that is committed to leveraging our innovative signaling pathway drug technologies in seeking to develop next generation targeted cancer therapies. In expanding our drug development efforts with respect to these targeted cancer programs, we are building upon our past experience in targeting signaling pathways, including the Hedgehog pathway. We seek to conduct research programs both internally and through strategic collaborations. Our most advanced program is our Hedgehog pathway inhibitor program under collaboration with Genentech, Inc., a wholly-owned member of the Roche Group. The lead drug candidate being developed under this program is GDC-0449, a first-in-class orally-administered small molecule Hedgehog pathway inhibitor. Genentech and Roche are responsible for the clinical development and commercialization of GDC-0449, and we are eligible to receive payments under the collaboration assuming the successful achievement by Genentech of specified regulatory objectives, and we are also eligible for a royalty on product sales of any products that are successfully commercialized and sold by Genentech.

President and Chief Executive Officer
Daniel R. Passeri
Number of Employees 34
Contact Information

45 Moulton St

Cambridge, Massachusetts 02138

curis.com

(617) 503-6500

NAICS Code Biological Product (except Diagnostic) Manufacturing: 325414

Recent Events

  • Curis Reports Third Quarter 2009 Financial Results

    10/29/09 - Joint Venture / Alliance - View Story

  • Curis shrinks 3Q loss as partnership revenue rises

    10/29/09 - Financial Announcement - View Story

  • Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305

    8/08/09 - Joint Venture / Alliance - View Story

  • Curis Reports Second Quarter 2009 Financial Results and Provides Pipeline Update

    7/30/09 - Financial Announcement - View Story

News & Analysis

curis inc. - All News and Analysis

Decision Makers

Name (plus bio) Position
Daniel R. Passeri President and Chief Executive Officer
Lee L. Rubin Executive Vice President of Research and Chief Scientific Officer
Michael P. Gray CFO & COO
Changgeng Qian Vice President, Discovery and Preclinical Development
Mark W. Noel Vice President Technology Management and Business Development
Mary Elizabeth Potthoff Vice President and General Counsel
Mitchell Keegan Vice President
George Vande Woude Director, Van Andel Research Institute
Andrew P McMahon
Brigid Hogan
Clifford J Tabin
Kenneth J Pienta Professor, Internal Medicine
Martin C Raff
Matthew Scott
Roeland Nusse Investigator
Samir Witta Clinical Assistant Professor
Thomas Jessell
Susan B. Bayh Director
Van Andel Director

Board of Directors

Name (plus bio) Position
Douglas A Melton Chair, Department of Molecular and Cellular Biology, Harvard University
James R McNab Chairman
Joseph M. Davie Chairman
Martyn D. Greenacre Chair
Stuart A Aaronson Chairman
George F Vande Woude Board of Directors
James R. Tobin Board of Directors
Kenneth I Kaitin Board of Directors
Stephen Carter Board of Directors

Mr. Passeri has served as our President and Chief Executive Officer and as a director since September 2001. From November 2000 to September 2001, Mr. Passeri served as our Senior Vice President, Corporate Development and Strategic Planning. From March 1997 to November 2000, Mr. Passeri was employed by GeneLogic Inc., a biotechnology company, most recently as Senior Vice President, Corporate Development and Strategic Planning. From February 1995 to March 1997, Mr. Passeri was employed by Boehringer Mannheim, a pharmaceutical, biotechnology and diagnostic company, as Director of Technology Management. Mr. Passeri received a J.D. from the National Law Center at George Washington University, an M.Sc. in biotechnology from the Imperial College of Science, Technology and Medicine at the University of London and a B.S. in biology from Northeastern University.

Organization Position Status
Curis, Inc. President and Chief Executive Officer Current
Prostate Cancer Survival Tips President and Chief Executive Officer, Curis, Inc. Current
Curis, Inc. Board of Directors Current
Boston Scientific Corporation Chief Executive Officer Former
Ore Pharmaceuticals Inc. Senior Vice President, Corporate Development and Strategic Planning Former
Boston Scientific Corporation Director, Applera Corporation Former
Boehringer Mannheim Director of Technology Management Former
Northeastern University J.D. Former
University of London Master of Science in Biotechnology Former
Northeastern University Bachelor of Science In Biology Former

Organization Position Status
Curis, Inc. Executive Vice President of Research and Chief Scientific Officer Current
Nyscf Board of Directors Current
University College London Senior Scientist Former
Betagenon Chairman of the Board Former
Cornell University doctorate in neuroscience at Rockefeller Former
The Rockefeller University Doctorate In Neuroscience Former

Mr. Gray has served as our Chief Operating Officer and Chief Financial Officer since December 2006. From December 2003 until December 2006, Mr. Gray served as our Vice President of Finance and Chief Financial Officer and served as our Senior Director of Finance and Controller from August 2000 until December 2003. Mr. Gray held financial positions including Controller and de Facto Chief Financial Officer at Reprogenesis, a predecessor biotechnology company, from January 1998 until July 2000. Mr. Gray previously served as an audit professional for the accounting and consulting firm of Ernst & Young, LLP. Mr. Gray is a certified public accountant, holds an M.B.A. from the F.W. Olin Graduate School of Business at Babson College, and has a B.S. in accounting from Bryant College.

Organization Position Status
Ernst & Young Former
Bryant College B.S. In Accounting Former

Dr. Qian joined Curis in 2001. He has over 25 years of academic and industrial experience in drug discovery, including pharmacokinetics, drug metabolism, efficacy evaluation, experimental disease model development and drug safety assessment. Prior to Curis, he played key role in the discovery of several anti-inflammation, anticancer and CNS drug candidates at CytoMed Inc., LeukoSite Inc., and Millennium Pharmaceuticals, Inc. He is an inventor on seven issued patents and six filed new patents, and he has authored over 20 scientific publications. Dr. Qian earned a Ph.D. in Pharmacology and an M.D. from the Hunan Medical University and has served as a professor of the University since 1992.

Organization Position Status
Curis, Inc. Vice President, Discovery and Preclinical Development Current

Mr. Noel has served as our Vice President, Technology Management and Intellectual Property since September 2008. From March 2001 until September 2008, Mr. Noel served as our Vice President, Technology Management and Business Development. From March 2000 to February 2001, Mr. Noel was employed by GeneLogic, as Vice President of Customer Relations. From January 1998 to February 2000, Mr. Noel was employed by GeneLogic as Senior Director of Program Management. From December 1993 to January 1998, Mr. Noel was employed by the National Cancer Institute’s Office of Technology Development (now the Technology Transfer Branch of the NCI Office of Technology and Industrial Relations), where from July 1997 to January 1998, he served as Acting Deputy Director. From February 1989 to November 1993, Mr. Noel worked as a patent agent at Gist Brocades NV, a supplier of ingredients to the pharmaceutical and food sectors. Mr. Noel holds a B.S. from the University of Maryland.

Organization Position Status
Curis, Inc. Vice President Technology Management and Business Development Current
Ore Pharmaceuticals Inc. Vice President of Customer Relations Former
Ore Pharmaceuticals Inc. Senior Director of Program Management Former
National Cancer Institute Former
University of Maryland B.S. Former

Organization Position Status
Curis, Inc. Vice President and General Counsel Current

Organization Position Status
Curis, Inc. Vice President Current

Organization Position Status
Curis, Inc. Director, Van Andel Research Institute Current
Curis, Inc. Board of Directors Current

Organization Position Status
Curis, Inc. Current
California Institute of Technology Postdoctoral Fellow Former
California Institute of Technology Staff Scientist Former
Columbia University Adjunct Professor Former
Harvard University Professor of Molecular and Cellular Biology Former
University College Ph.D. Former
University of Oxford B.A. in Zoology Former

Organization Position Status
Curis, Inc. Current
Vanderbilt University Medical Center Former

Organization Position Status
Curis, Inc. Current
Massachusetts Institute of Technology Adjunct Professor of Health Sciences and Technology Former
Harvard Medical School Professor of Genetics Former
Massachusetts General Hospital Former
Massachusetts Institute of Technology Ph.D. in Biological Sciences Former

Dr. Pienta is Professor of Internal Medicine and Urology and the Director of the Urologic Oncology program at the University of Michigan Comprehensive Cancer Center. He is also the chair of the Translational Medicine Committee of the Southwest Oncology Group (SWOG). Dr. Pienta has international expertise in the development of novel chemotherapeutic programs for prostate cancer and is the principal investigator on The University of Michigan's SPORE (Specialized Program of Research Excellence) in prostate cancer awarded from the National Cancer Institute. In 2003, Dr. Pienta received the American Cancer Society Clinical Research Professor Award in recognition of his achievements in translational research. He is the author of more than 200 peer-reviewed articles and 50 book chapters. Currently, Dr. Pienta is involved in research to understand the process of prostate cancer metastasis to bone as well as developing new therapies for prostate cancer.

Organization Position Status
Curis, Inc. Professor, Internal Medicine Current
Curis, Inc. Chair Current
Curis, Inc. Board of Directors Current
Wayne State University School of Medicine Assistant Professor Former

Organization Position Status
National Academy of Sciences Foreign Associate Current
Sciences, Inc Associate Current
First Arvo / Champalimaud Current
Instant Notes Current
Garland Science Current
Champalimaud Foundation Current
The American Society for Cell Biology Current
Curis, Inc. Current
The Royal Society Board of Directors Current
The American Academy of Arts Board of Directors Current
The Ellison Medical Foundation Board of Directors Current
Myelin Repair Foundation Board of Directors Current
Sciences, Inc Board of Directors Current
The American Academy of Arts Member Current
Sciences, Inc Member Current
The Royal Society Fellow Current
University College London Professor of Biology Former
Royal Victoria Hospital Former
Massachusetts General Hospital Former
McGill University M.D. Degrees Former
McGill University B.S. Former

Organization Position Status
Curis, Inc. Current
Massachusetts Institute of Technology PhD Former

Organization Position Status
Curis, Inc. Investigator Current

Samir E. Witta, M.D., Ph.D., joined Rocky Mountain Cancer Centers in July of 2005. Originally from the Czech Republic, Dr. Witta specializes in hematology and medical oncology and practices at the RMCC Lakewood location. He is a Clinical Assistant Professor at University of Colorado where he is involved in translational research.Dr. Witta graduated from medical school at the First Faculty of Medicine,Charles University in Prague. Dr. Witta earned his Ph.D. in genetics and developmental biology at the First Faculty of Medicine, Charles University and at National Institutes of Health in Bethesda, Maryland. Dr. Witta went onto complete his residency in internal medicine at The Northeastern Pennsylvania Affiliated Residency Program. He then did a fellowship in hematology and medical oncology at the University of Colorado Health Sciences Center in Denver. Dr. Witta is a member of the American Society of Clinical Oncology.

Organization Position Status
Curis, Inc. Clinical Assistant Professor Current
Rocky Mountain Cancer Centers Current
American Society of Clinical Oncology Board of Directors Current
Curis, Inc. Board of Directors Current

Thomas M. Jessell, Ph.D. is an Investigator of the Howard Hughes Medical Institute and Professor of Biochemistry and Molecular Biophysics at Columbia University College of Physicians and Surgeons. Dr. Jessell's lab examines how neurons in the vertebrate central nervous system (CNS) are generated and interconnected, focusing on circuits formed between sensory and motor neurons in the spinal cord.

Organization Position Status
Columbia University College of Physicians and Surgeons Professor of Biochemistry and Molecular Biophysics Current
Curis, Inc. Current
Nyscf Board of Directors Current
Harvard Medical School Assistant Professor Former
Cambridge University Ph.D. in neuropharmacology Former

Organization Position Status
Curis, Inc. Chair, Department of Molecular and Cellular Biology, Harvard University Current
Stowers Institute for Medical Research Member of the Stowers Institute Scientific Advisory Board Current
Curis, Inc. Director Former
Trinity College Ph.D. In Molecular Biology Former
Cambridge University Ph.D. Former
University of Illinois Bachelor's Degree In Biology Former

Mr. McNab serves as Chairman and CEO of eNOS Pharmaceuticals. He has started several successful companies including Parker Medical, manufacturer and worldwide supplier of orthopedic and sports-related products. Reprogenesis, Inc., a regenerative therapy company that merged into Curis, Inc. (NASDAQ: CRIS), and Sontra Medical, Inc., a privately held ultrasound-based diagnostics and transdermal delivery company. His expertise consists of management and development of intellectual property assets, development of corporate strategies, managing growth, and utilizing capital markets. Mr. McNab serves on the Board of Directors at Curis, Inc. and at Sontra Medical. Mr. McNab received a B.A. in Economics from Davidson College and a M.B.A. from the University of North Carolina at Chapel Hill.

Organization Position Status
Enos Pharmaceuticals, Inc Chairman and CEO Current
The Sentinel Associate Current
Sentinel Capital Partners Associate Current
Edgeview Partners LLC Current
Curis, Inc. Chairman Current
Argolyn Bioscience, Inc. Director Current
Echo Therapeutics, Inc. Founder Former
Wachovia Securities, LLC summer intern Former
Echo Therapeutics, Inc. chairman Former
Curis, Inc. Board of Directors Former
The University of North Carolina MBA Former
The University of North Carolina at Chapel Hill M.B.A. Former
Davidson College BA Degree In History Former

Organization Position Status
Stratatech Corporation Dr. Davie Was Vice President Current
Midwest Warehousing, LLC Partner Current
Lifeheart.Com Director of Cv Therapeutics Current
Rivervest Venture Management, LLC Advisor Current
Haynes Capital Corp Current
Curis, Inc. Chairman Current
Ocera Therapeutics, Inc. Board of Directors Current
Keel Pharmaceuticals, Inc. Board of Directors Current
Targeted Genetics Corporation Board of Directors Current
Myelin Repair Foundation Board of Directors Current
Stratatech Corporation Board of Directors Current
Washington University School of Medicine Board of Directors Current
Ranexa Director Current
Bg Medicine, Inc. Director Current
Pathway 2 Curis Board of Directors Current
Epitome Biosystems Board of Directors Current
Inflazyme Pharmaceuticals Ltd Director Current
Gentiae Clinical Research, Inc. Director Current
Washington University School of Medicine senior vice president, research Former
Biogen, Inc. Senior Vice President, Research Former
Biogen Idec, Inc. senior vice president, research Former
Biogen, Inc. Vice President of Research Former
Washington University School of Medicine Professor Former
Genetics, Inc. Former
Indiana University Ph.D. In Bacteriology Former
Washington University MD Former
Washington University School of Medicine M.D. Former
Indiana University M.A. Former
Washington University School of Medicine A.B. Former
Indiana University A.B. Former

Since July 2004, Mr. Greenacre has served as Chairman of Beijing Med-Pharm Corporation, a pharmaceutical company. Mr. Greenacre also has served since 2002 as Chairman of Life Mist Technologies, Inc., a fire suppression equipment company. From 1997 to 2001, Mr. Greenacre served as Chief Executive Officer and director of Delsys Pharmaceutical Corporation, a formulation and drug delivery system company. From 1993 to 1997, Mr.

Organization Position Status
Life Mist Technologies, Inc. Chairman Current
Curis, Inc. Chair Current
BMP Sunstone Corporation Chairman of the Board Current
Lifemist Chairman Current
Pathway 2 Curis Board of Directors Current
Personalized Medicine Coalition Board of Directors Current
Cephalon, Inc. Board of Directors Current
Acusphere, Inc. Director Current
BMP Sunstone Corporation Committee Member Current
GlaxoSmithKline Plc Chairman Former
Creative BioMolecules, Inc. Director Former
BMP Sunstone Corporation Board of Directors Former
Curis, Inc. Director Former
Orchestra Therapeutics, Inc. Director Former

Dr. Aaronson is currently the Chairman for the Department of Oncological Sciences at The Mount Sinai Medical Center in New York City, and the Jane B. and Jack R. Aron Professor of Neoplastic Diseases at the school. He has been recognized for his accomplishments throughout the years with numerous awards and medals, including the Distinguished Service Medal Award from the U.S. Public Health Service, the Rhoads Memorial Award from the American Association of Cancer Research and the Paul Erhlich Prize from Germany. Dr. Aaronson is the author of more than 530 publications, an inventor on more than 50 patents and serves on numerous editorial boards and scientific advisory committees.

Organization Position Status
Curis, Inc. Chairman Current
Curis, Inc. Board of Directors Current

Organization Position Status
Cell Cycle LLC Board Member Current
Curis, Inc. Board of Directors Current
Molecular Imaging Corp Board Member Current
National Cancer Institute Former
Cancer Research Board Member Former

Mr. Tobin has served as President and Chief Executive Officer of Boston Scientific Corporation, a medical device manufacturer, since March 1999. Mr. Tobin previously served as President and Chief Executive Officer of Biogen, Inc., a biotechnology company, from 1997 to 1998 and President and Chief Operating Officer from 1994 to 1997. Prior to joining Biogen, he held various positions at Baxter International Inc., including President and Chief Operating Officer from 1992 to 1994. Mr. Tobin is also a director of Boston Scientific and Curis, Inc.

Organization Position Status
Celera Genomics Current
Applied Biosystems Group Co-Chair Current
Applera Corporation Board Member Current
Curis, Inc. Board of Directors Current
Beth Israel Deaconess Medical Center Board Member Current
Biogen Idec, Inc. Chief Executive Officer Former
Biogen, Inc. Chief Executive Officer Former
Boston Scientific Corporation President & Chief Executive Officer Former
Biogen Idec, Inc. President Former
Biogen, Inc. President Former
Baxter International Inc. President Former
Curis, Inc. President Former
Biogen Idec, Inc. Chief Operating Officer Former
Baxter International Inc. Chief Operating Officer Former
Biogen, Inc. Chief Operating Officer Former
Baxter International Inc. Executive Vice President Former
Baxter International Inc. Managing Director Former
Guidant Corporation Director, President & CEO Former
U.S. Navy Lieutenant Former
Baxter International Inc. NA Former
Curis, Inc. Chair Former
Creative BioMolecules, Inc. Board of Directors Former
Boston Scientific Corporation Board of Directors Former
Biogen, Inc. Director Former
Applied Biosystems Group Board of Directors Former
Harvard Business School M.B.A Former
Harvard College A.B Former

Organization Position Status
Tufts University School of Medicine Assistant Professor of Pharmacology Current
Bio-IT World, Inc. Director Current
Pharma, Inc. Board of Directors Current
Curis, Inc. Board of Directors Current
Whitman Consulting Group, Inc. Director Current
Recherche Clinique Director Current
Cambridge Bio Collabrative Inc. Director Current
Pharmcentric Director Current
Nehi Director Current
Clarix Ivrs and Edc Director Current
Chen Pr, Inc. Director Current
University of Rochester M.S. and Ph Former
Cornell University B.S. Former

Organization Position Status
Curis, Inc. Board of Directors Current

Organization Position Status
Emmis Communications Corporation Visiting Prof, Butler University Current
Pathway 2 Curis Board of Directors Current
WellPoint, Inc. Board of Directors Current
Dendreon Corporation Director Current
Curis, Inc. Director Current
Hereditary Angioedema Board of Directors Current
MDRNA, Inc. Board of Directors Current
Emmis Communications Corporation Director Current
Dyax Corp. Director Current
International Commission Commissioner Former
Eli Lilly and Company Attorney Former
Butler University Distinguished Visiting Professor Former
Cubist Pharmaceuticals, Inc. Former
Golden State Foods Director Former
University of Southern California Law Center J.D. Former
University of Southern California School of Law J.D. Former
University of California, Berkeley B.A. Former
University of California B.S. Former

Organization Position Status
Curis, Inc. Director Current

Executive News

  • Curis Announces GDC-0449 Phase I Clinical Data Published in New England Journal of Medicine

    Business Wire - 9/03/09 - View Story

  • Curis to Present at the Rodman & Renshaw 11th Annual Healthcare Conference

    Business Wire - 9/02/09 - View Story

  • Peter Dreier: Turn Up the Heat on the Insurance Industry

    Huffington Post - 8/24/09 - View Story

  • UPDATE 1-Leerink Swann raises Boston Scientific to outperform

    Forbes.com - 8/18/09 - View Story

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     CRIS $2.70 +0.44 (19.47% )
Average Volume 530,344
Shares Outstanding 66.57M
Market Cap 179.7M
Year High 2.74
Year Low 0.68
Earnings Per Share -0.14
P/E Ratio -19.29
Dividend N/A
Yield N/A
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