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denosumab

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Amgen Reports Positive Data at ASCO from Three Studies of Denosumab in Cancer Patients
Phase 2 Study of Patients Previously Treated with IV Bisphosphonates Showed Denosumab Reduced Bone Resorption and Skeletal-Related Events
Tags: Amgen Inc., Denosumab, patient
Research articles 2008-05-31
Amgen and Daiichi Sankyo Announce Agreement for Denosumab in Japan
Amgen Grants Daiichi Sankyo Exclusive Rights to Develop and Commercialize Denosumab in Japan
Tags: agreement, Amgen Inc., Denosumab
Research articles 2007-07-11
Biotech's New Blockbusters -- Oh, Really?
FierceBiotech's Maureen Martino has produced a "special report" that four biotech drugs poised for approval later this year could be "the next generation of biologic blockbusters" -- that is, treatments that not only pull in more than $1 billion in annual sales, but which "could offer real breakthroughs for patients"...
Tags: Amgen Inc., Blockbuster, FierceBiotech, Synagis, Denosumab, Golimumab, Biotechnology, David P. Hamilton
Blog posts 2008-07-10

Additional Resources

Cutting Edge Information's Research on Monoclonal Antibodies Drives Forecasts for the Oncology Market
By 2012, sales of monoclonalantibodies will represent nearly 50% of oncology drug sales, according to anew study by Cutting Edge Information. Successful brands such as Rituxan, Herceptin and Erbitux are all expectedto grow by anywhere from 23% to 80% by 2013. Furthermore, there areseveral monoclonal antibodies, such as Amgen's...
Articles 2008-07-30
Amgen Announces Positive Top-Line Results for Denosumab Pivotal Postmenopausal Osteoporosis Trial
Study Met Primary Endpoint of Reducing New Vertebral Fractures and Secondary Endpoints of Reducing Time to First Non-Vertebral and Hip Fractures Adverse Events Similar to Placebo THOUSAND OAKS, Calif. -- Amgen (NASDAQ: AMGN) today announced findings from the pivotal fracture trial evaluating its RANK Ligand inhibitor,...
Articles 2008-07-25
Company highlight: Amgen Inc
Thousand Oaks based Amgen Inc. saw a 7.4% rise in its stock price over the two weeks ending July 16. On July 11, the company announced that it had reached an agreement to settle its outstanding antitrust litigation with Ortho Biotech Products L.P. On July 14, the company also announced...
Articles 2008-07-21
Examine the Monoclonal Antibodies Report: 2008 Update
Reportlinker.com announces that a new market research report related to the Pharmaceutical industry industry is available in its catalogue. Monoclonal Antibodies Report: 2008 Update - Detailed analysis of the monoclonal antibody segment, encompassing market dynamics, key therapy areas, technology and target types through to 2013, evaluating the...
Articles 2008-06-25
Zacks Bull and Bear of the Day Highlights: ConocoPhillips, General Motors, Amgen, Web.com and Oxford Industries
CHICAGO -- Zacks Equity Research highlights ConocoPhillips (NYSE: COP) as the Bull of the Day and General Motors (NYSE: GM) as the Bear of the Day. In addition, Zacks Equity Research provides analysis on Amgen, Inc. (Nasdaq: AMGN), Web.com (Nasdaq: WWWW) and Oxford Industries (NYSE: OXM). ...
Articles 2008-06-13
Interim Phase 2 Results of Open-Label Clinical Trial of Denosumab in Giant Cell Tumor of Bone Demonstrated 87 Percent Response Rate
Giant Cell Tumor is a Rare Bone Tumor Afflicting Younger Adults For Which Few Treatment Options Exist ABSTRACT NUMBER: 10500 CHICAGO -- Amgen (NASDAQ:AMGN) today announced interim results of an open-label Phase 2 study demonstrating a positive response rate to administration of denosumab in subjects with...
Articles 2008-05-31
Amgen Reports Positive Data at ASCO from Three Studies of Denosumab in Cancer Patients
Phase 2 Study of Patients Previously Treated with IV Bisphosphonates Showed Denosumab Reduced Bone Resorption and Skeletal-Related Events Comparison of Phase 2 Studies Showed Consistent Reduction of Bone Resorption with Denosumab in either Bisphosphonate-Naive or -Treated Patients Sub-group Analysis of Phase 3 Study Showed Denosumab Increased...
Articles 2008-05-31
Amgen to Webcast Investor Meeting at Upcoming American Society of Clinical Oncology Conference
THOUSAND OAKS, Calif. -- Amgen (NASDAQ:AMGN) will webcast its investor meeting at the upcoming American Society of Clinical Oncology ASCO Conference on Sunday, June 1 at 8 p.m. Central Time. Members of Amgen's scientific and management team will participate at the meeting. The company plans to highlight key compounds in...
Articles 2008-05-29
Denosumab Achieved Superior Bone Mineral Density Gains in Head-to-Head Trial versus Weekly Alendronate
Phase 3 Study Showed Bone Mineral Density Gains at All Skeletal Sites Measured with Denosumab Administration BARCELONA, Spain -- Amgen (NASDAQ: AMGN) today announced complete results from a head-to-head, double-blind study comparing the effects of twice-yearly subcutaneous injections of denosumab versus weekly oral doses of alendronate (FOSAMAX([R])) on...
Articles 2008-05-28
Amgen Announces Webcast to Discuss Results of denosumab Phase 3 Head-to-Head Study versus alendronate at the Upcoming European Symposium on Calcified Tissues Conference
THOUSAND OAKS, Calif. -- Amgen (NASDAQ:AMGN) today announced that it will hold a conference call on Wednesday, May 28, 2008, beginning at 8 a.m. Eastern Time to discuss the results of the denosumab Phase 3 head-to-head study versus alendronate (the "141" study) at the upcoming European Symposium on Calcified Tissues...
Articles 2008-05-27
Denosumab Osteoporosis Study Meets Primary and All Secondary Bone Mineral Density Endpoints in Alendronate Transition Study
Patients Transitioned from Alendronate to Denosumab Therapy Achieved Superior Gains in Bone Mineral Density Versus Those Continuing on Alendronate Therapy THOUSAND OAKS, Calif. -- Amgen (NASDAQ: AMGN) today announced findings from a head-to-head, double-blind trial comparing the effects of denosumab in post-menopausal women with low bone mass transitioned...
Articles 2008-05-19
Amgen Highlights Data to Be Presented at ASCO
New Data from Denosumab, Vectibix([R]) and Mid-Stage Pipeline Demonstrate Progress of Oncology Portfolio THOUSAND OAKS, Calif. -- Amgen (NASDAQ:AMGN) today announced it will present new data from the Company's oncology portfolio on both approved and investigational cancer therapies at the 2008 American Society of Clinical Oncology ASCO Annual...
Articles 2008-05-16
Pivotal Phase 3 Data Show Denosumab Increased Bone Density at Multiple Skeletal Sites in Early and Later Stage Postmenopausal Women
Overall Incidence of Adverse Events Similar Between Denosumab and Placebo Groups THOUSAND OAKS, Calif. -- Amgen (NASDAQ: AMGN) today announced the publication of results from its 24-month, 332-patient Phase 3 pivotal study in women with early and late stage postmenopausal osteoporosis in the Journal of Clinical Endocrinology and...
Articles 2008-04-02
Novel osteoporosis treatments show promise
SAN FRANCISCO -- A number of novel treatments for osteoporosis are under investigation, and one of them might even provide a cure for the disease, Dr. Steven R. Cummings said at a meeting on osteoporosis sponsored by the University of California, San Francisco. Dr. Cummings, director of the...
Articles 2008-02-15
Denosumab Osteoporosis Study Met Primary and All Secondary Bone Mineral Density Endpoints in a Head-to-Head Comparison with Weekly Alendronate
THOUSAND OAKS, Calif. -- Amgen (NASDAQ:AMGN) today announced findings from a head-to-head, double-blind study comparing the effects of twice-yearly subcutaneous injections of denosumab versus weekly oral doses of alendronate (FOSAMAX([R])) on bone mineral density BMD in postmenopausal women with low bone mineral density. The study met primary and all secondary...
Articles 2008-01-24
Denosumab protects bone in patients treated for breast Ca
SAN ANTONIO -- The novel bone-strengthening agent denosumab markedly increased bone mineral density at both trabecular and cortical sites throughout the skeleton in its first phase III clinical trial in breast cancer patients on adjuvant aromatase inhibitor therapy, Dr. Georgiana K. Ellis reported at the annual San Antonio Breast Cancer...
Articles 2008-01-15
Pivotal Phase 3 Data Show Denosumab Increased Bone Density Throughout Skeleton in Non-Metastatic Breast Cancer Patients on Adjuvant Aromatase Inhibitor Therapy
A Study Evaluating Twice Yearly Dosing with Denosumab Met All Primary and Secondary Endpoints SAN ANTONIO -- Amgen (NASDAQ:AMGN) today announced results of the first Phase 3 pivotal study to complete in the denosumab oncology development program. The study evaluated denosumab's effect on bone density across the skeleton...
Articles 2007-12-15
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