engineering and harvard college

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Normalization of Joint Image-Intensity Statistics in MRI Using the Kullback-Leibler Divergence

This paper describes a novel algorithm for altering global intensity statistics of magnetic resonance images MRI to fit a model distribution while preserving local feature contrast. The algorithm estimates a multiplicative correction field that alters the intensity statistics of an image or set of images to best match those of...

Tags: Peripherals, Engineering, Scanners, Hardware, Harvard College, Algorithm

White papers 2004-06-17

Virtual Cystoscopy: Color Mapping of Bladder Wall Thickness

Three-dimensional visualization with virtual endoscopy of the bladder appears to be a promising tool for screening and follow up of cancer. Vining reported a sensitivity of only 23% in detecting tumors smaller then 5mm using virtual cystoscopy. To improve identification of these lesions we developed an algorithm for color mapping...

Tags: Harvard College, President, Engineering, Algorithm

White papers 2003-04-18

Statistical Validation of Automated Probabilistic Segmentation Against Composite Latent Expert Ground Truth in MR Imaging of Brain Tumors

The validity of segmentation is an important issue in image processing because it has a direct impact on surgical planning. Binary manual segmentation is not only time-consuming but also lacks the ability of differentiating subtle intensity variations among voxels, particularly for those on the border of a tumor and for...

Tags: Harvard College, Engineering, Segmentation

White papers 2002-11-13

Advanced Nonrigid Registration Algorithms for Image Fusion

Medical images are brought into spatial correspondence, or aligned, by the use of registration algorithms. Nonrigid registration refers to the set of techniques that allow the alignment of datasets that are mismatched in a nonrigid or non-uniform manner. Such misalignments can result from physical deformation processes, or can be a...

Tags: Harvard College, Algorithm, Nonrigid Registration, Nonrigid Deformation, Productivity, Engineering

White papers 2002-11-11

Validation of Image Segmentation and Expert Quality With an Expectation-Maximization Algorithm

Characterizing the performance of image segmentation approaches has been a persistent challenge. Performance analysis is important since segmentation algorithms often have limited accuracy and precision. Interactive drawing of the desired segmentation by domain experts has often been the only acceptable approach, and yet suffers from intra-expert and inter-expert variability. Automated...

Tags: Segmentation, Harvard College, Algorithm, Variability, Performance Analysis, Engineering

White papers 2002-10-24

Incorporating Non-Rigid Registration Into Expectation Maximization Algorithm to Segment MR Images

The paper introduces an algorithm which allows the automatic segmentation of multi channel magnetic resonance images MRI. They extended the Expectation Maximization-Mean Field Approximation (EM-MF) Segmenter, to include Local Prior Probability Maps. Thereby their algorithm estimates the bias field in the image while simultaneously assigning voxels to different tissue classes...

Tags: Algorithm, Harvard College, Engineering

White papers 2002-03-05

Real-Time Registration of Volumetric Brain MRI by Biomechanical Simulation of Deformation During Image Guided Neurosurgery

The key challenge faced by a neurosurgeon is the removal from the brain of as much tumor tissue as possible while minimizing the removal of healthy tissue and avoiding the disruption of critical anatomical structures. They developed an algorithm to create enhanced visualizations of tumor and critical brain structures by...

Tags: Harvard College, Brain, Engineering

White papers 2001-12-14

A Binary Entropy Measure to Assess Nonrigid Registration Algorithms

Assessment of normal and abnormal anatomical variability requires a coordinate system enabling inter-subject comparison. This paper presents a binary minimum entropy criterion to assess affine and nonrigid transformations bringing a group of subject scans into alignment. This measure is a data-driven measure allowing the identification of an intrinsic coordinate system...

Tags: Algorithm, President, Harvard College, Engineering

White papers 2001-12-05

Deformation Analysis for Shape Based Classification

Statistical analysis of anatomical shape differences between two different populations can be reduced to a classification problem, i.e., learning a classifier function for assigning new examples to one of the two groups while making as few mistakes as possible. In this framework, feature vectors representing the shape of the organ...

Tags: Difference, Harvard College, Analysis, Engineering

White papers 2001-09-14

A Novel Nonrigid Registration Algorithm and Applications

This paper describes about a new algorithm for nonrigid registration of brain images based on an elastically deformable model. The use of registration methods has become an important tool for computer-assisted diagnosis and surgery. The goal of this paper was to improve analysis in various applications of neurology and neurosurgery...

Tags: Algorithm, Harvard College, Engineering, Productivity

White papers 2001-08-23

Intraoperative Segmentation and Nonrigid Registration for Image Guided Therapy

This paper discusses about the goal to improve image guidance during minimally invasive image guided therapy by developing an intraoperative segmentation and nonrigid registration algorithm. The algorithm was designed to allow for improved navigation and quantitative monitoring of treatment progress in order to reduce the time required in the operating...

Tags: Segmentation, Algorithm, Harvard College, Therapy, Engineering

White papers 2000-08-02

Automatic Nonrigid Registration for Tracking Brain Shift During Neurosurgery

Intraoperative imaging is used more frequently today since this enables the surgeon to localize structures inside the brain more accurately and helps to detect shape changes. In order to combine information's derived at different time points, it describes a nonrigid registration algorithm that aligns MR scans of the brain. Based...

Tags: Harvard College, Brain, Document Management, Engineering, Enterprise Software, Software, Finance, Managerial Accounting

White papers

Unsupervised and Adaptive Segmentation of Multispectral 3D Magnetic Resonance Images of Human Brain: A Generic Approach

This paper provides a generic algorithm for the segmentation of three dimensional multi-spectral magnetic resonance images. The algorithm is unsupervised and adaptive, does not require initialization, classifies the data in any number of tissue classes and suggests an optimal number of classes. It uses a statistical model including Bayesian distributions...

Tags: Segmentation, Algorithm, Intensity, Harvard College, Brain, Classification, Engineering

White papers

Additional Resources

Ban legacy preferences

There is no good argument for a legacy preference in college admissions. Legacies are less qualified and perform less well academically than their non-legacy peers. The preference is inefficient for fundraising, and it undermines the role of colleges as engines of socioeconomic opportunity. Schools should do away with it voluntarily,...

Articles 2008-08-20

McDonald's® Funds $100,000 Scholarships to Four Hispanic Students

RMHCR/HACERR Awards More Than $17.9 Million in 23-year Commitment to Higher Education OAK BROOK, Ill., July 7 /PRNewswire/ -- McDonald's announced today the selection of four Hispanic high school seniors who will each receive a college scholarship of $100,000 to fulfill their college dreams....

Articles 2008-07-07

Valtech Hires Bud Phillips as VP, Transformation Services

DALLAS -- Valtech, Inc. (www.valtech.us) an international software development provider of OnDemand[TM] solutions and Agile and Lean coaching, training, and business process management today announced that Howard "Bud" Phillips has joined the company as VP of transformation services. Valtech's transformation services helps clients translate their business requirements...

Articles 2008-07-02

Investment Firm Allied Minds to Commercialize New Frozen Aliquotter Technology with Two Local Major Universities

Harvard University and Northeastern University Technology Receive Funding From Allied Minds to Commercialize Novel Technology for the Extraction of Aliquots BOSTON, July 2 /PRNewswire/ -- Allied Minds, a pre-seed investment corporation specializing in early stage university business ventures, Harvard University's Office of Technology Development,...

Articles 2008-07-02

PR Newswire Summary of Technology Copy, July 1, 2008

Following is a summary of high technology news releases transmitted today by PR Newswire. The full text of these releases is available at the PR Newswire for Journalists, http://media.prnewswire.com/. CLTU011 07/01/2008 00:01 r f TOKYO-InComm-iTunes TOKYO InComm Technology Drives iTunes Card Sales at...

Articles 2008-07-01

Taking a Look at Our Economic Woes

‘A New Kind of Recession’: Readers offered their own analyses of the plummeting consumer confidence that has weakened the U.S. economy. Coping with costly fuel, one reader said, “I’m driving my car only to and from work and trying to combine my errands.” Some emphasized the need to...

Articles 2008-06-30

McDonald's® Funds $100,000 Scholarships to Four Hispanic Students

RMHCR/HACERR Awards More Than $17.9 Million in 23-year Commitment to Higher Education OAK BROOK, Ill., June 26 /PRNewswire/ -- McDonald's announced today the selection of four Hispanic high school seniors who will each receive a college scholarship of $100,000 to fulfill their college dreams....

Articles 2008-06-26