Concordant with its widespread use, hormone therapy was among the most heavily promoted medications prior to the WHI E+P report. Following reporting of the evidence of harm from this trial, there was a substantial decline in promotional spending for hormone therapy, particularly for the agents most directly implicated in the...
Patients with growth hormone deficiency GHD frequently report to suffer from an impaired Quality of Life QoL and growth hormone GH substitution is found to improve this. However, the same test may be used for measuring QoL, well-being or health status in different studies. The most important in the appraisal...
In this article Millennium Pharmaceuticals, Inc. discusses their preliminary results from a phase I clinical trial of MLN2704 in patients with progressive metastatic hormone- refractory prostate cancer. The findings from the study indicated that MLN2704 was very well tolerated and produced antitumor activity, including one partial response in a patient...
Bryan Czyzewski submits: Cougar Biotechnology CGRB is a publicly traded company focused on developing novel treatments for cancer. The company is developing CB7630 Abiraterone Acetate, a small molecule for the treatment of hormone refractory prostate cancer [HRPC], and has completed several clinical trials demonstrating its efficacy. The National Cancer Center...
The Find: Recent research finds that male hormones might help explain the risk-taking behavior that underlies market bubbles and crashes The Source: Research from the University of Cambridge in this week's edition of Proceedings of the National Academy of Sciences. The Takeaway: Women...
Biotechnology is increasingly regarded upon as an important reservoir for the development of new and innovative but generally expensive, pharmaceuticals. This paper studies the process of assessment and diffusion of biotechnology drugs by studying three cases, i.e. nebacumab, colony stimulating factors and recombinant human growth hormone. These cases are evaluated...
Without question, hormone replacement therapy has become the most controversial issue in menopausal gynecology. The WHI study was designed in 1991-1992 to determine the role of long-term therapy with either unopposed estrogen ET or combined estrogen and progestin EPT in postmenopausal women's health. For the evaluation of long-term ET, the...
Erythropoietin Epo is a hormone that can be misused for doping. The detection of its recombinant form rEpo involves analysis of Epo chemiluminescence images containing bands. The paper describes an alternative classification method, based on self-organizing map, and is proposed to solve the task of separation. The method performs well,...
Low profitability in the beef industry, coupled with changes in consumer tastes and preferences, have led some producers to look at niche markets. Increased demand for natural and organic foods, product innovation, competition, recent changes in USDA quality certification programs, and the beef hormone dispute are all positive drivers of...
The World Trade Organization WTO trade decisions affect all aspects of social, political, and economic life, subjecting national policies and programmes to the disciplining principles and values set out in its various agreements. Accordingly, the result has been a growing tension between the need to establish universal rules and the...
The United States produced 170.3 billion pounds of milk in 2003. Just one-third of the milk is processed into fluid milk and cream products. Total beverage milk in 2001 totaled 6.3 billion gallons. Organic milk accounts for less than 1 percent of the milk market. USDA standards for organic food...
A. Reza Saadat submits: Diabetes is a tough market to compete in for any company. Insulin is the standard therapy for most patients with severe Diabetes. It is a naturally occurring hormone and it exists as both short acting and long acting therapy. It requires close monitoring as it...
Is the asterisk coming to the business world? The use of performance-enhancing drugs has clogged up the sports world for the last couple of years, but steroid and human growth hormone are not the only way to get a chemical advantage. What about the brain drugs, those...
Howard Sun submits: Recent studies have shown a direct positive correlation between testosterone levels and financial risk taking, and a direct negative correlation between cortisol levels and risk. This would probably not be a surprise to most people. A study published in PNAS Proceedings of the National Academy of Sciences...
Whenever oil prices spike, energy companies like Exxon come in for even more criticism than usual. The public is generally a bit more forgiving of food companies – that is, up to a point. With the government reporting that food inflation is as bad as it has been in nearly...
How can you condemn cheating in a game where the players are expected to "steal" bases? David Jacobson has done a remarkable job in researching and writing this week's business of baseball feature package, talking about salaries, the revenue sharing model and the MLB's legally sanctioned monopoly...
Biotech's New Blockbusters -- Oh, Really?20 to 30 Blockbusters of Biotech Exist NowInnovation in Pharmacology?Beginning in the 1970, biopharmaceuticals were being researched for conceptual production in those places once called academic institutions. The first biopharmaceutical ever was a synthetic insulin called Humulin made by Genetech in 1982. Later...
Express Scripts Fine Settles PBM Mess -- For NowPBMsPublished on discoverwhatyouthink.blogspot.comThe Amazement and the Price of Innovation: PBMsRecently, you may have heard or read in mass media sources about the issue of what are known as pharmacy benefit managers that have clients who are prescribed medications created by what...
