Orchestra Therapeutics Inc.

James B. Glavin has 38 years of experience in the health care pharmaceutical industry. He has been Chairman of the Board of Directors of Immune Response since May 1993, CEO from April 1987 to September 1994, President from October 1987 to September 1994, and Treasurer from April 1987 to May 1991. He was Chairman of the Board of Directors of Smith Laboratories, Inc., a medical products company, from September 1985 to May 1990 and Acting President and CEO from September 1985 to August 1989. During 1985 to 1987 Mr. Glavin was a Partner in CH Ventures. From 1981 to 1983, he was President and CEO of Genetics Systems Corporation and Chairman of the Board from 1983 to 1985. In addition to being Director and Chairman of Immune Response, he is currently a Director of Nektar Therapeutic Systems, Inc., formerly Inhale Therapeutic Systems, Inc., Meridian Fund, and Chairman of the Board of Avanir Pharmaceuticals.

Dr. Perelman has served as a member of Immusol's Board of Directors since 1996. Dr. Perelman began his career in 1957 as an organic chemist and held a number of positions at Eli Lilly & Co. (Lilly), including serving as President of Lilly International. From 1986 until his retirement in 1993, Dr. Perelman served as Executive Vice President of Lilly and President of Lilly Research Laboratories. He was a member of the Lilly Board of Directors and its Executive Committee from 1976 to 1993. Dr. Perelman received a bachelor's degree in chemistry from Northwestern University and a Ph.D. in organic chemistry from Rice University. Currently, Dr. Perelman is a Director at Immune Response Corporation, a biotech company and Inhale Therapeutics Systems, Inc., a drug delivery system company.

Robert E. Knowling, Jr. is CEO of the Leadership Academy, City of New York Department of Education, and he serves as chairman of the board of The Immune Response Corporation. Previously, he was chairman and CEO of SimDesk Technologies, Inc. (formerly Internet Access Technologies, Inc.). Mr. Knowling began his career in 1977 at Indiana Bell and progressed rapidly through assignments in operations, engineering and marketing. He was assigned to Ameritech's re-engineering breakthrough development team in 1992 and was named vice president of Network Operations for Ameritech in 1994. Mr. Knowling joined U S WEST in 1996 as vice president of Network Operations. In 1997 he was named executive vice president of Operations and Technologies, responsible for a 30,000-member team in charge of planning, delivering and maintaining high-quality telecommunications services. In 1998, he joined Covad Communications as chairman, president and CEO. In recognition for his spirit and mission of inclusion, opportunity, expansion, advocacy and success in the workplace, he was awarded the Wall Street Project's Reginald Lewis Trailblazers Award by President Clinton and the Rev. Jesse Jackson in 1999. He serves on the board of directors for HP and Heidrick & Struggles International, Inc. He is on the advisory boards for Ontologent, Inc.; Northwestern University's Kellogg Graduate School of Management; and the University of Michigan Graduate School of Business. Mr. Knowling received a BA in theology from Wabash College and an MBA from Northwestern University's Kellogg Graduate School of Business.