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Superposition State Molecular Dynamics
The ergodic sampling of rough energy landscapes is crucial for understanding phenomena like protein folding, peptide aggregation, polymer dynamics, and the glass transition. These rough energy landscapes are characterized by the presence of many local minima separated by high energy barriers, where Molecular Dynamics MD fails to satisfy ergodicity. To...
Ternary Complexes Comprising Polyphosphoramidate Gene Carriers With Different Types of Charge Groups Improve Transfection Efficiency
To understand the influence of charge groups on transfection mediated by polymer complexes, we have synthesized a series of biodegradable and cationic polyphosphoramidates PPAs with an identical backbone but different side chains. The mechanism of enhancement in transfection efficiency by the mixture carriers appears to be unrelated to the particle...
Thermodynamic Measurements and Predictions of the Adsorption of Short-Chain Peptides on Nanothin Polymer Films
This contribution describes experimental measurements of sub molecular-level interaction energies involved in the process of peptide adsorption on polymer films. The objective of this study was to use surface plasmon resonance SPR spectroscopy to measure the Gibbs energy change on adsorption Gad for pairs of various homopeptides on highly uniform,...
Polymer-Dispersed Bicontinuous Cubic Glycolipid Nanoparticles
The paper reveals that certain amphiphilic polymers such as PEO-PPO-PEO triblock copolymer PL can directly disperse a cubic glycolipid, 1-O-phytanyl--D-xyloside (-XP), into bicontinuous cubic nanoparticles in water medium. The use of synchrotron small-angle X-ray diffraction SSAXD permitted the identification of the exact structure of these dispersed particles in the colloidal...
Poly(ethylene oxide sulfide): New Poly(ethylene glycol) Derivatives Degradable in Reductive Conditions
Poly ethylene oxide sulfide PEOS, polymers consisting of an internal ethylene oxide oligomer and disulfide linkage, were synthesized and characterized. The degree of polymerization was dependent upon temperature, dimethyl sulfoxide condition, and monomer hydrophobicity. The stability of PEOS was measured by the size exclusion chromatography method after the incubation both...
Liquid-Liquid Equilibrium Data, Viscosities, and Densities of Aqueous Mixtures of Poly(propylene glycol) With Tri-sodium Citrate at 298.15 K
Aqueous two-phase systems, which are useful for the separation of biological products from the complex mixtures in which they are produced,1,2 can be made from aqueous solutions of two water-soluble polymers or a polymer and a salt. Poly ethylene glycol PEG is often used in this technique, and there are...
Mechanism of Optically Inscribed High-Efficiency Diffraction Gratings in Azo Polymer Films
According to this paper, both volume refractive index and surface profile diffraction gratings could be laser inscribed in azo polymer thin films. The mechanism for the high-efficiency photoinduced surface gratings appears to be isomerization driven mass transport, with grating depths of up to 1 m achievable with films of an...
In Situ Immobilization of Proteins and RGD Peptide on Polyurethane Surfaces via Poly(ethylene oxide) Coupling Polymers for Human Endothelial Cell Growth
This white paper reveals about the pre-SMA synthesis and PEU surface modification that were characterized using nuclear magnetic resonance spectroscopy (1H NMR), attenuated total reflection infrared spectroscopy (ATR-FTIR), and X-ray photoelectron spectroscopy XPS. The cell morphologies were investigated by optical inverted microscopy OIM and scanning electrical microscopy SEM. The gelatin-...
New Polymer Synthesis by Nitroxide Mediated Living Radical Polymerizations
This white paper considers radical polymerization which may be considered a mature technology with millions of tons of vinyl based homo- and copolymers being produced annually. This perception of maturity is based on the fact that free radical polymerization is so widely used industrially and in research laboratories for the...
PUBLICATIONS - Polymeric drug delivery
Polymeric Drugs and Drug Administration, ed. Raphael M. Ottenbrite, American Chemical Society (1994), ISBN 0-8412-2744-6, $69.95 Aimed at academic and industrial polymer and pharmaceutical chemists, scientists working with drug delivery systems in humaPolymeric Drugs and Drug Administration, ed. Raphael M. Ottenbrite, American Chemical Society (1994), ISBN...
Additional Resources
Rohm and Haas to Present New Findings in Rubber-to-Metal Bonding Technology
PHILADELPHIA -- Technical experts from specialty materials company Rohm and Haas (NYSE:ROH) will present new findings and introduce new products related to rubber-to-metal bonding at the upcoming 174th Technical Meeting and Rubber Mini Expo[TM]. The Expo is sponsored by the Rubber Division, American Chemical Society ACS and will be held...
Biothera Develops New Method for Analyzing Beta Glucan Structure
Presented at International Carbohydrate Symposium and American Chemical Society EAGAN, Minn. -- Biothera has developed a new analytical method to characterize a key structural attribute of beta 1,3/1,6 glucans, which will aid researchers developing this immune-enhancing carbohydrate for pharmaceutical applications. The method was presented recently to...
Better organic semiconductors
Researchers from Korea's Seoul National University SNU and the US National Institute of Standards and Technology NIST have learned how to tweak a new class of polymer-based semiconductors to better control the location and alignment of the components of the blend. Their recent findings, namely how to move...
50 Making a Difference profile: Elizabeth A. Nalley, Cameron
Those who can - do, and they also teach, at least if you're Dr. Elizabeth Nalley. Serving as a chemistry professor at Cameron University for the past 39 years is only the tip of the iceberg when it comes to Nalley's influence on past and future generations. ...
Protein Research Marketing Insights
ARLINGTON, Va., Sept. 23 /PRNewswire/ -- BioInformatics, LLC (http://www.gene2drug.com/), the leading market research and consulting firm serving the life science industry, announces the publication of its latest report, "Protein Research: Strategies for Marketing to Chemists and Biologists." A joint effort between BioInformatics, LLC and the American Chemical...
2008 Ad
PHILADELPHIA -- Rohm and Haas Company is accepting entries into its 2008 poster contest. The deadline for entries is Friday, Sept. 26. The theme of the contest, "Having a Ball With Chemistry" builds from the American Chemical Society's theme for its 2008 National Chemistry Week campaign. U.S. students...
Nanoparticles conspire with free radicals: dose of carcinogens could be comparable to smoking
PHILADELPHIA -- The daily exposure to free radicals from car exhaust, smokestacks and even your neighbors' barbecue could be as harmful as smoking, according to a new study. Many combustion processes, such as those in a car engine, create tiny particles that may act as brewing pots and carriers for...
Letters to the Editor
Supply, demand Re: "As chemists gather, let's refocus efforts to gain diversity in science," Tuesday: Catherine T. Hunt, past president of the American Chemical Society, plays a familiar refrain. Her message is that we need more students especially women and minority students to take up science, technology, engineering, and mathematics...
Albemarle Scientists Named 'Heroes of Chemistry'
BATON ROUGE, La., Aug. 21 /PRNewswire-FirstCall/ -- Twelve scientists from specialty chemical maker Albemarle Corporation and ExxonMobil Research and Engineering Company were honored by the American Chemical Society ACS in a special ceremony Sunday night as "Heroes of Chemistry" for their work in the development of NEBULAR...
Spoonful of Sugar Really Might Help Medicine Go Down
If your child won't take medicine and shuns broccoli at the dinner table, his body may just be hard-wired to respond that way. "Kids reject the bad taste of medicine, because it's basic biology. Their system is designed to reject that taste, because many toxic substances are bitter and distasteful,"...
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Professional Organizations: 813920
