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- High-throughput Detection of Polymorphisms in Genes Encoding Inflammatory Proteins Using Microfluidic Arrays
- B-44L. Chen1, S. A. Lagerstedt1, S. E. Peterson1, B. A. Dukek1, J. L. Jones1, W. J. Sandborn2, D. J. O'kane1, J. P. McConnell1. 1 Mayo Clinic College of Medicine, Department of Laboratory Medicine and Pathology, Rochester, MN, 2 Mayo Clinic College of Medicine, Department of Gastroenterology and Hepatology Rochester, MN,Backyround:...
- Research articles 2006-06-01
- Osta Biotechnologies Inc. Announces Promising Clinical Results
- MONTREAL -- From its Study Conducted in Collaboration with Helsinki University, Finland, for the Development of a Novel Prognostic Blood Test for Osteoporosis Osta Biotechnologies Inc. (TSX VENTURE:OBI) today announced promising results of its clinical study for the development of a novel prognostic blood test...
- Research articles 2006-03-14
- Osta Biotechnologies Inc. Announces Promising Clinical Results.
- MONTREAL, QUEBEC, Mar 14, 2006 CCNMatthews via COMTEX -- From its Study Conducted in Collaboration with Helsinki University, Finland, for the Development of a Novel Prognostic Blood Test for Osteoporosis Osta Biotechnologies Inc. (TSX VENTURE:OBI) today announced promising results of its clinical study for...
- Research articles 2006-03-14
- VARIAGENICS Announces Licensing Agreement With Celera Diagnostics for MTHFR Patents
- Business Editors and Health/Medical Writers BIOWIRE2K CAMBRIDGE, Mass.--BUSINESS WIRE--Jan. 14, 2003 VARIAGENICS, INC. (Nasdaq:VGNX), an emerging molecular diagnostics company and leader in pharmacogenomics, today announced that it has granted a worldwide license relating to its MTHFR methylenetetrahydrofolate reductase patent rights to Celera Diagnostics, a joint venture between...
- Research articles 2003-01-14
- University of California obtains United States patent.(Brief Article)
- University of California (Oakland, CA) has patented a method of screening large, complex, polyexonic eukaryotic genes such as the ATM gene for mutations and polymorphisms by an improved version of single strand conformation polymorphism electrophoresis that allows electrophoresis of two or three amplified segments in a...
- Research articles 2002-09-01
- A Microsatellite Marker for Tagging Dn2, a Wheat Gene Conferring Resistance to the Russian Wheat Aphid.
- The Russian wheat aphid RWA, Diuraphis noxia Mordvilko, is an economically important pest of wheat (Triticum aestivum L.). An effective means to control the RWA is through the use of resistant cultivars. While a phenotype-based selection has been useful for selection of resistant plants, it has inherent limitations. Screening can...
- Research articles 2001-09-01
- Valuable Arabidopsis data released through unique public-private partnership.
- M2 PRESSWIRE-1 June 2000-US NSF: Valuable Arabidopsis data released through unique public-private partnership C1994-2000 M2 COMMUNICATIONS LTD RDATE:31052000 New data that will allow researchers to isolate essentially any gene in Arabidopsis, a mustard plant that serves as a model organism...
- Research articles 2000-06-01
- Association between apolipoprotein A2 MspI polymorphism and hypertriglyceridemia in Koreans
- S.H. HONG, B.Y. KANG, W.H. PARK, J.Q. KIM, AND C.C. LEE Abstract In view of the possible involvement of apolipoprotein A2 (apoA2) in lipoprotein metabolism, we investigated the association between genetic variation of the APOA2 gene and lipid levels in Korean subjects with hypertriglyceridemia. The MspI rare allele (M-) frequency...
- Research articles 1998-02-01
- VNTR polymorphism in the Buenos Aires, Argentina, metropolitan population
- ANDREA SALA, GUSTAVO PENACINO, AND DANIEL CORACH1 Abstract VNTR loci provide a wealth of information for human genetic research, ranging from gene mapping to paternity testing and forensic identification. In this study we report the construction, validation, and analysis of the first local genetic database for VNTR markers for Argentina....
- Research articles 1997-12-01
- Genetic relationships among soybean plant introductions with resistance to soybean cyst nematodes.
- Soybean [Glycine max (L.) Merr.] cultivars in the USA, which are resistant to soybean cyst nematode SCN Heterodera glycines Ichinohe, have resistance derived from only a few plant introductions PIs. Many other SCN resistant PIs have been identified which could be used as sources for broadening the diversity of resistance...
- Research articles 1997-11-01
- New data for AG haplotype frequencies in caucasoid populations and selective neutrality of the AG polymorphism
- The apolipoprotein B100-related AG system is highly polymorphic in human populations and can be useful for anthropological studies (Breguet et al. 1990). A few years after the discovery of the first isoprecipitin AGA and its association with low-density lipoproteins LDLs (Allison and Blumberg 1961), 10 AG antigens, named X, Y,...
- Research articles 1994-02-01
- Design and application of microsatellite marker panels for semiautomated genotyping of rice (Oryza sativa L.). (Cell Biology & Molecular Genetics).
- The objective of this study was to develop a systematic and flexible method for assembling multiplex simple sequence repeat SSR marker panels for high throughput genome analysis in rice, Oryza sativa, and to test these panels on a set of cultivated ri The objective of this study was to...
- Research articles 2002-11-01
- Genomic polymorphism identifies a subtilisin-like protease near the Rhg4 locus in soybean.(Genomics, Molecular Genetics & Biotechnology)
- Soybean [Glycine max (L.) Merr.] germplasm PI 437654 exhibits broad resistance to soybean cyst nematode (Heterodera glycines Ichinohe, SCN). Probes derived from PI 437654 bacterial artificial chromosome BAC done 15G19 at the Rhg4 locus detected a rest Soybean [Glycine max (L.) Merr.] germplasm PI 437654 exhibits broad resistance to...
- Research articles 2004-01-01
- Chromosomal polymorphism as detected by C-banding patterns in Chilean alfalfa germplasm (1). (Cell Biology & Molecular Genetics).
- A cytogenetic investigation was conducted on the tetraploid alfalfa [Medicago satira subsp. sativa (L.) L. & L.] Chilean germplasm source PI 536534 using the combined techniques of C-banding and image analysis. Cluster and multiple correspondence an A cytogenetic investigation was conducted on the tetraploid alfalfa [Medicago satira subsp. sativa...
- Research articles 2002-07-01
- A Universal Method for Automated Gene Mapping
- This paper reveals that small insertions or deletions InDels constitute a ubiquitous class of sequence polymorphisms found in eukaryotic genomes. Here, the paper present an automated high-throughput genotyping method that relies on the detection of fragment-length polymorphisms FLPs caused by InDels. The protocol utilizes standard sequencers and genotyping software. It...
- White papers 2005-01-17
- A Prospective Study of XRCC1 (X-Ray Cross-Complementing Group 1) Polymorphisms and Breast Cancer Risk
- The gene XRCC1 (X-Ray Repair Cross-Complementing Group 1) encodes a protein involved in DNA base excision repair. Two non-synonymous polymorphisms in XRCC1 (Arg194Trp and Arg399Gln) have been shown to alter DNA repair capacity in some studies in vitro. This paper examines the association between polymorphisms in XRCC1 and breast cancer...
- White papers 2005-11-21
- What Is the Impact of the ACE Gene Insertion/Deletion (I/D) Polymorphism on the Clinical Effectiveness and Adverse Events of ACE Inhibitors? - Protocol of a Systematic Review
- This white paper deals with a protocol that describes a strategy to quantify the effect modification of the ACE polymorphism on ACE inhibitors in relevant clinical domains using meta-epidemiological research methods. The results may provide evidence for the usefulness of pharmacogenetic testing for individualized ACE inhibitor therapy. The Angiotensin Converting...
- White papers 2004-09-10
- Neural Network Analysis in Pharmacogenetics of Mood Disorders
- This white paper study deals with testing a neural network strategy for a combined analysis of two gene polymorphisms. A Multi Layer Perceptron model showed the best performance and was therefore selected over the other networks. The polymorphism in the transcriptional control region upstream of the 5HTT coding sequence SERTPR...
- White papers 2004-12-09
Additional Resources
- Celera Identifies FCAR Genetic Polymorphism Associated with Increased Risk for Myocardial Infarction
- Individuals With FCAR Genetic Polymorphism Derive Better Than Average Protection from Statin Therapy Study Confirms Genetic Basis for Individuals at Elevated Risk for Heart Attack Who Derive Better Than Average Protective Benefits of Statin Treatment ROCKVILLE, Md. -- Celera Genomics (NYSE:CRA), an Applera Corporation business, today announced a...
- Research articles 2006-09-28
- Environmental Polymorphism Registry: banking DNA to discover the source of susceptibility
- Walking outside on a day when ozone levels are at "code orange" doesn't bother one person, but for someone else, it can result in chest pain, coughing, wheezing, or lung and nasal congestion. Why? Polymorphisms, tiny interindividual variations in genes, may be part of the reason. Providing a pool of...
- Research articles 2006-07-01
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