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rna

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Glaxo Boosts Biotech With Regulus Deal: By Ben Hirschler LONDON (Reuters UK) - GlaxoSmithKline GSK boosted its position in biotech on Thursday by signing a deal that could be worth up to $600 million (303 million pounds) with Regulus Therapeutics, taking it into the hot area of RNA technology. The tie-up covers...; Tags: RNA, Inflammation, Regulus Therapeutics, MicroRNAs, Biotechnology, Alnylam Pharmaceuticals Inc., GlaxoSmithKline Plc., Isis Pharmaceuticals Inc.; News items 2008-04-17
Rapid, Single-Tube Method for Quantitative Preparation and Analysis of rna and DNA in Samples as Small as One Cell: This paper introduces a novel and highly reliable single-tube method for rapid cell lysis, followed by quantitative preparation and analysis of both RNA and/or DNA molecules in small samples. In contrast to previous approaches, this procedure allows all steps to be carried out by sequential dilution in a single tube,...; Tags: Biotechnology, BioMed Central, RNA, molecule, DNA, analysis; White papers 2005-01-13
DNA-Free rna Preparations From Mycobacteria: To understand mycobacterial pathogenesis analysis of gene expression by quantification of RNA levels becomes increasingly important. However, current preparation methods yield mycobacterial RNA that is contaminated with chromosomal DNA. After sonication of RNA samples from Mycobacterium smegmatis genomic DNA is efficiently removed by DNaseI in contrast to untreated samples. This...; Tags: Biotechnology, BioMed Central, RNA, DNA, analysis; White papers 2004-11-30
rna Interference: Learning Gene Knock-Down From Cell Physiology: Over the past decade RNA interference RNAi has emerged as a natural mechanism for silencing gene expression. This ancient cellular antiviral response can be exploited to allow specific inhibition of the function of any chosen target gene. RNAi is proving to be an invaluable research tool, allowing much more rapid...; Tags: Biotechnology, BioMed Central, gene, RNA, biology, tool; White papers 2004-11-22
Co-Transcriptional Folding Is Encoded Within rna Genes: The main aim of this work is to study if and how co-transcriptional folding is encoded within the primary and secondary structure of RNA genes. In order to achieve this, the paper presents the known primary and secondary structures of a comprehensive data set of 361 RNA genes as well...; Tags: Biotechnology, BioMed Central, RNA, gene; White papers 2004-08-05

In Vitro Chondrogenesis of Bone Marrow-Derived Mesenchymal Stem Cells in a Photo Polymerizing Hydrogel: Mesenchymal stem cells MSCs from skeletally mature goats were encapsulated in a photopolymerizing polyethylene glycol-based hydrogel and cultured with or without transforming growth factor b1 TGF to study the potential for chondrogenesis in a hydrogel scaffold system amenable to minimally invasive implantation. Chondrogenic differentiation was evaluated by histological, biochemical, and...; Tags: Biotechnology, RNA, photograph; White papers 2003-09-25

Additional Resources

Invitrogen Scientists Link microrna Sequences to Cancer Using rna Samples from BioServe: CARLSBAD, Calif. & BELTSVILLE, Md. -- In research demonstrating that RNA previously thought to have no biological relevance may be of use for therapeutic and diagnostic targets, Invitrogen Corporation (NASDAQ:IVGN), a provider of essential life science technologies for research, production and diagnostics, and BioServe, the leading provider of clinically annotated...; Articles 2008-05-07
Genta Announces Transfer of its Common Stock to the OTC Bulletin Board: BERKELEY HEIGHTS, N.J., May 6 /PRNewswire-FirstCall/ -- Genta Incorporated (BULLETIN BOARD: GNTA) announced today that it has been advised that the Financial Industry Regulatory Authority (FINRA, formerly, the NASD) has cleared a market maker's Form 211 application to quote the Company's stock on the Over-the-Counter Bulletin Board...; Articles 2008-05-06
Regulus Therapeutics Exclusively Licenses Intellectual Property from Stanford University Relating to microrna Antagonists to Treat Inflammatory Diseases: CAMBRIDGE, Mass. & CARLSBAD, Calif. -- Regulus Therapeutics LLC, a joint venture between Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY) and Isis Pharmaceuticals, Inc. (Nasdaq: ISIS) formed to discover, develop, and commercialize microRNA miRNA therapeutics, announced today that it has obtained exclusive rights from Stanford University to worldwide patent applications covering methods...; Articles 2008-05-06
Roche Research Director Grace Ju Hailed as NJABR 'Outstanding Woman of Science': NUTLEY, N.J., May 2 /PRNewswire/ -- Roche is pleased to announce that Grace Ju, Ph.D., research director, RNA Therapeutics Discovery Research at Roche, was honored as an "Outstanding Woman of Science" by the New Jersey Association of Biomedical Research NJABR at its 2008 Red Carpet Thank You Research Gala...; Articles 2008-05-02
Third Wave to Present at 33rd Annual Deutsche Bank Health Care Conference: MADISON, Wis. -- Third Wave Technologies Inc. (NASDAQ:TWTI) today announced that it will present at the 33rd Annual Deutsche Bank Health Care Conference, which is being held May 5-7, 2008, at the InterContinental Hotel in Boston. Maneesh K. Arora, Third Wave's senior vice president and chief financial officer, will make...; Articles 2008-05-01
Antisense Therapy against CCR3 and the Common Beta Chain Attenuates Allergen-induced Eosinophilic Responses: Rationale: The drug product TPI ASM8 contains two modified phosphorothioate antisense oligonucleotides designed to inhibit allergic inflammation by down-regulating human CCR3 and the common beta chain (β^sub c^) of IL-3, IL-5, and granulocyte-macrophage colony-stimulating factor receptors. Objectives: This study examined the effects of inhaled TPI ASM8 on sputum cellular...; Articles 2008-05-01
Inflammasome mrna Expression in Human Monocytes during Early Septic Shock: Rationale: Monocytes are central to the initiation of the inflammatory response in sepsis, with caspase-1 activation playing a key role. Monocyte deactivation during sepsis has been linked to poor outcomes. Objectives: Given the importance of caspase-1 in the immune response, we investigated whether monocytes from patients early in septic...; Articles 2008-05-01
Genetic Tool facilitates experimental processes: Designed as single benchtop solution for genetic research, Geniom RT Analyzer[R] provides sample loading, staining, and detection. Analyzer features freely programmable temperature control that optimizes hybridization and enables use of enzymatic reactions directly on microfluidic array for signal enhancement and primer extension assays. It handles broad spectrum of DNA and...; Articles 2008-04-30
Alnylam to Webcast Presentation at the Deutsche Bank 33rd Annual Health Care Conference: CAMBRIDGE, Mass. -- Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, today announced that management will present a company overview at the Deutsche Bank 33rd Annual Health Care Conference on Tuesday, May 6, 2008, at 9:30 a.m. ET at the InterContinental Hotel in Boston, Mass. A...; Articles 2008-04-30
Cequent Pharmaceuticals' Johannes Fruehauf, MD, Ph.D., to be Featured Speaker at rnai World Congress in Boston - May 2, 2008: CAMBRIDGE, Mass., April 30 /PRNewswire/ -- Cequent Pharmaceuticals, a pioneer in the development of novel products to deliver RNAi-based treatments to prevent and treat human disease, announced that its Vice President of Research, Johannes Fruehauf, MD, Ph.D., is slated to speak at the RNAi World Congress meeting in Boston....; Articles 2008-04-30
Ontario Ministry of Health Uses Seegene to Effectively Screen Multiple Respiratory Pathogens in a Single Test: Seegene today announced that the MolecularDiagnostic Branch of the Ministry of Health and Long-Term Care for Ontario,Canada's most densely populated province, is reporting excellent resultsfrom public screenings for respiratory virus and pneumobacter detectionusing the company's "Seeplex" Respiratory diagnostic test. Seegene's Seeplex respiratory test is helping the Province of Ontario carryout...; Articles 2008-04-28
Rosetta Genomics Announces Expansion of its Microrna Intellectual Property Estate: Rosetta Genomics In-Licenses, on a Non-Exclusive Basis, Proprietary MicroRNAs for Research Applications From Rockefeller University Following This Agreement, Rosetta Genomics has Access to a Full Range of Potential MicroRNA Applications Based on These MicroRNAs REHOVOT, Israel and JERSEY CITY, New Jersey, April 28 /PRNewswire-FirstCall/ --...; Articles 2008-04-28
Pharmasset Presents Results of 4-Week Combination Study of R7128 for the Treatment of Chronic Hepatitis C: - 85% of patients achieve undetectable HCV RNA levels following 4 weeks of treatment with R7128 1500mg BID with PegasysR plus CopegusR - - Safety and tolerability comparable to placebo administered with Pegasys plus Copegus - - EASL presentation available on Pharmasset website - ...; Articles 2008-04-25
Alnylam to Webcast Presentation at the Morgan Stanley Global Healthcare Unplugged Conference: CAMBRIDGE, Mass. -- Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, today announced that management will present a company overview at the Morgan Stanley Global Healthcare Unplugged Conference on Friday, May 2, 2008, at 9:50 a.m. ET at The Ritz-Carlton in Key Biscayne, Florida. A live...; Articles 2008-04-25

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