Takeda Pharmaceutical Company Ltd.

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Jacques is head of our Paris office corporate group. He specialises in corporate M&A work and in EU competition and merger issues, working also out of the firm's Brussels office. His client base includes a wide range of European, Japanese, American and global blue-chip companies including TUI, Takeda Pharmaceutical, Total, Belgacom, M-real and Toyota Motor Corporation.

Masahiro Fujimaki serves as the Executive Vice President of Takeda Pharmaceuticals North America (TPNA), Inc. In this role, Fujimaki is responsible for supervising and directing all of the business affairs of TPNA in accordance with the Board of Directors' corporate directives. Specifically, in cooperation with TPNA's parent company, Takeda Pharmaceutical Company Limited (TPC), Fujimaki is responsible for overseeing the development and operations of the corporate infrastructure of TPNA. In addition, he takes an executive role in the development of corporate policies relating to all internal departments and functions. Fujimaki has worked for more than 18 years with TPC. During that time, Fujimaki held progressively responsible managerial positions and has gained considerable experience in the international management and marketing of Takeda's pharmaceutical products. His Takeda experience includes several successful roles in the Domestic Marketing and Sales Division, and Corporate Strategy and Planning Department. More recently, Fujimaki worked as a manager of Division of Americas in charge of two affiliates in the U.S. as well as licensee business in North and South American countries. Fujimaki earned a bachelor's degree in economics from Keio University of Tokyo.

Nick Manusos serves as Vice President of Business Development at Takeda Pharmaceuticals North America (TPNA), Inc. Manusos joined TPNA in July of 2006. His responsibilities include directing Takeda's efforts in partnerships, licensing and alliance management in North America as well as for global Takeda business. Prior to joining TPNA, Manusos worked at TAP Pharmaceutical Products Inc. for six years. TAP is a joint venture of Japan-based Takeda Pharmaceutical Company Limited (TPC) and Abbott Laboratories. He joined TAP as licensing director in 2000. In that role, Manusos oversaw or personally executed domestic and international research collaborations, technology and device licensing and co-promotion and pharmaceutical compound licensing. Manusos was promoted to vice president of licensing and business development in April of 2004 and was responsible for leading the licensing and business development team and the alliance management team in building TAP's portfolio of products. Manusos joined the Ross Products division of Abbott in 1983. He held various business and operations management positions at Abbott, including business director of Global Generics and Custom Pharma within Abbott's Specialty Products division, and general manager of Abbott Animal Health. He currently sits on the executive board of the Opera Theatre North. Manusos earned a bachelor of business administration degree in operations management from the University of Wisconsin - Whitewater and a master's degree in business administration at the Kellogg School of Management.

James Tyree is senior vice president, Pharmaceutical Operations Tyree first joined Abbott from 1978 until 1979 as a business analyst for a year. He rejoined the company in June 1997 and has been in various management positions including divisional vice president and general manager for Abbott's international division in Japan. He recently served as vice president, global licensing/new business development in the Pharmaceutical Products Division. He assumed his current role in 2006. Prior to re-joining Abbott in 1997, Tyree was president of Sugen Inc., a biotechnology start-up company and held various leadership positions at other pharmaceutical companies. He serves on the board of directors for TAP Pharmaceuticals, a joint venture between Abbott and Takeda Pharmaceutical Company Limited. He is a member of the advisory boards of the Polsky Center of Entrepreneurship at the University of Chicago and the Kellogg Center for Biotechnology at Northwestern University. He is a member of Richard M. Daley's Chicago Mayor's Council of Technology Advisors. Formerly chairman, he is also chairman of the board of directors of the Illinois Biotechnology Industry Organization. He earned bachelor's degrees in psychology and forensic studies and a master's degree in business administration from Indiana University.